alexa A Semi-Empirical Approach to Estimate Kinetic Parameters for the Batch and Continuous Settling of Flocculating Yeast Slurries
ISSN: 2155-9821

Journal of Bioprocessing & Biotechniques
Open Access

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Research Article

A Semi-Empirical Approach to Estimate Kinetic Parameters for the Batch and Continuous Settling of Flocculating Yeast Slurries

Samuel Conceicao Oliveira1* and Reinaldo Giudici2

1Department of Bioprocesses and Biotechnology, Faculty of Pharmaceutical Sciences, UNESP, Rodovia Araraquara-Jaú km 1, Araraquara, Sao Paulo, Brazil

2Department of Chemical Engineering, Polytechnic School, University of Sao Paulo-USP, Av. Prof. Luciano Gualberto, Travessa 3, Sao Paulo, Brazil

*Corresponding Author:
Samuel Conceicao Oliveira
Department of Bioprocesses and Biotechnology
Faculty of Pharmaceutical Sciences, UNESP
Rodovia Araraquara- Jaú km 1, Araraquara, Sao Paulo, Brazil 14800-903
Tel: +551633014646
E-mail: [email protected]

Received Date: November 22, 2016; Accepted Date: November 28, 2016; Published Date: November 29, 2016

Citation: Oliveira SC, Giudici R (2016) A Semi-Empirical Approach to Estimate Kinetic Parameters for the Batch and Continuous Settling of Flocculating Yeast Slurries. J Bioprocess Biotech 6:290. doi: 10.4172/2155-9821.1000290

Copyright: © 2016 Oliveira SC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



The knowledge of sedimentation kinetics is a necessary requisite for an adequate design of settlers aiming the separation and recovery of yeasts in alcoholic fermentation processes. In this study, batch and continuous settling tests were performed using slurries of flocculating yeasts obtained from the fermentation of sugarcane juice in a tower reactor with cell recycling. The batch tests were conducted in a 250 mL cylindrical glass vessel with initial concentrations of yeast between 90 and 100 g/L by measuring the variation over time of the height of the interface between the clarified liquid and the thickened slurry. These data were conveniently converted into cell concentration of the thickened sludge and a semi-empirical equation was developed to estimate the kinetic parameters of the settling. Data taken in a continuous settler in two continuous fermentation systems of different scales with cell recycle were also well fitted by the semi-empirical equation, but the adjusted parameters were different from those obtained for the batch tests.


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