A Small Sample Retrospective Study of Non-Infarct-Related Artery Simultaneous Revascularization during Primary Percutaneous Coronary Intervention for St-Segment Elevation Myocardial Infarction
|Yu Huang1,2, Chang-Wu Ruan2, Deng-Hai Zhang2, Gang Lin3 and Xiang-Jun Yang1*|
|1Department of Cardiology, the First Affiliated Hospital of Soochow University, Jiangsu Province, China|
|2Department of Cardiology, Shanghai Pudong District Gongli Hospital, China|
|3Department of Cardiology, the First People's Hospital of Nantong City, Jiangsu Province, China|
|Corresponding Author :||Xiang-Yun Yang
Department of Cardiology, the First Affiliated
Hospital of Soochow University, No.188 Shizi Street
Suzhou 215006, Jiangsu Province, China
E-mail: [email protected]
|Received: February 01, 2016 Accepted:February 16, 2016Published: February 26, 2016|
|Citation: Huang Y, Ruan CW, Zhang DH, Lin G, Yang XJ (2016) A Small Sample Retrospective Study of Non-Infarct-Related Artery Simultaneous Revascularization during Primary Percutaneous Coronary Intervention for St-Segment Elevation Myocardial Infarction. J Clin Exp Cardiolog 7:419. doi:10.4172/2155-9880.1000419|
|Copyright: © 2016 Huang Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
Objective: In patients with acute myocardial infarction (AMI) and multivessel coronary disease undergoing primary percutaneous coronary intervention (PCI), we compare the major cardiovascular events and plasma inflammatory markers (hsCRP, sCD40L, IL-6, and TNF-a) after treatment with simultaneous complete revascularization or culprit-only primary angioplasty.
Method: From June 2011 to June 2014, a total of 74 patients with AMI and multivessel coronary disease in our hospital underwent primary PCI, and among them 24 (32%) patients underwent simultaneous complete revascularization (complete PCI group) and 50 (68%) patients underwent culprit-only primary angioplasty (culpritonly group), then underwent PCI for the non-infarct-related artery at 1-4 weeks after primary PCI. The outcome was compared between the two groups one year after treatment.
Result: There was no significant difference in the incidence of major adverse cardiovascular events (non-fatal myocardial infarction, target vessel repeat revascularization, and cardiac death) between the two groups at one year (P > 0.05). The changes of these inflammatory markers were not statistically significant between the two groups (P > 0.05).
Conclusion: Compared to the culprit-only group, the complete PCI group had similar incidences of major adverse cardiovascular events (non-fatal myocardial infarction, target vessel repeat revascularization, all-cause and cardiac mortality). The present study suggests it was safe to intervene the non-infarct-related artery simultaneously during primary PCI. The elevated inflammatory marker levels were reduced in both groups, but the changes of these markers were not significantly different, so the long-term effects of these two PCI procedures are similar.