alexa A Small Sample Retrospective Study of Non-Infarct-Relat
ISSN: 2155-9880

Journal of Clinical & Experimental Cardiology
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Research Article

A Small Sample Retrospective Study of Non-Infarct-Related Artery Simultaneous Revascularization during Primary Percutaneous Coronary Intervention for St-Segment Elevation Myocardial Infarction

Yu Huang1,2, Chang-Wu Ruan2, Deng-Hai Zhang2, Gang Lin3 and Xiang-Jun Yang1*
1Department of Cardiology, the First Affiliated Hospital of Soochow University, Jiangsu Province, China
2Department of Cardiology, Shanghai Pudong District Gongli Hospital, China
3Department of Cardiology, the First People's Hospital of Nantong City, Jiangsu Province, China
Corresponding Author : Xiang-Yun Yang
Department of Cardiology, the First Affiliated
Hospital of Soochow University, No.188 Shizi Street
Suzhou 215006, Jiangsu Province, China
Tel: +86-0512-65223637
Fax: +86-0512-65223637
E-mail: [email protected]
Received: February 01, 2016 Accepted:February 16, 2016Published: February 26, 2016
Citation: Huang Y, Ruan CW, Zhang DH, Lin G, Yang XJ (2016) A Small Sample Retrospective Study of Non-Infarct-Related Artery Simultaneous Revascularization during Primary Percutaneous Coronary Intervention for St-Segment Elevation Myocardial Infarction. J Clin Exp Cardiolog 7:419. doi:10.4172/2155-9880.1000419
Copyright: © 2016 Huang Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

Objective: In patients with acute myocardial infarction (AMI) and multivessel coronary disease undergoing primary percutaneous coronary intervention (PCI), we compare the major cardiovascular events and plasma inflammatory markers (hsCRP, sCD40L, IL-6, and TNF-a) after treatment with simultaneous complete revascularization or culprit-only primary angioplasty.
Method: From June 2011 to June 2014, a total of 74 patients with AMI and multivessel coronary disease in our hospital underwent primary PCI, and among them 24 (32%) patients underwent simultaneous complete revascularization (complete PCI group) and 50 (68%) patients underwent culprit-only primary angioplasty (culpritonly group), then underwent PCI for the non-infarct-related artery at 1-4 weeks after primary PCI. The outcome was compared between the two groups one year after treatment.
Result: There was no significant difference in the incidence of major adverse cardiovascular events (non-fatal myocardial infarction, target vessel repeat revascularization, and cardiac death) between the two groups at one year (P > 0.05). The changes of these inflammatory markers were not statistically significant between the two groups (P > 0.05).
Conclusion: Compared to the culprit-only group, the complete PCI group had similar incidences of major adverse cardiovascular events (non-fatal myocardial infarction, target vessel repeat revascularization, all-cause and cardiac mortality). The present study suggests it was safe to intervene the non-infarct-related artery simultaneously during primary PCI. The elevated inflammatory marker levels were reduced in both groups, but the changes of these markers were not significantly different, so the long-term effects of these two PCI procedures are similar.

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