A Study to Assess the Anti Cholinergic Burden Index among Geriatrics
Background: Older cohorts often present with multiple co morbid conditions, for which polypharmacy become inevitable. Geriatrics’ also present with altered kinetics and dynamic changes. Polypharmacy together with their altered pharmacokinetic and pharmacodynamic changes among frail old patients’ results in adverse drug reactions and also imparts drug burden to them. Aim: The aim of this retrospective pilot study is to analyse the drug burden (DBI) and anti cholinergic burden (ACB) index experienced by the geriatric cohorts. Materials and Methods: In this retrospective pilot study, the medical records of patients’ aged 60 years and above were collected. Their demographics, medical and medication history were collected and analysed for co morbidity index, anti cholinergic burden and drug burden index. Results: In this retrospective pilot study, 104 patients’ were recruited, of which 59.61 % were males and 40.38% were females. The average co morbidity index was 2.29 ± 1.5. The average drug burden index owing to anti cholinergics and sedatives was found to be 0.34 ± 0.33 and 0.26 ± 0.29 respectively. Conclusion: The drug burden and anti cholinergic burden index substantiate that geriatrics with polypharmacy are in increased risk of cognitive and functional decline. Pharmacists’ and physicians should work coherently and incorporate guidelines proposed by experts while prescribing for geriatric people.