alexa Abnormal Endocrine and Behavioural Sleep Markers in a Child with Williams Syndrome and Siblings
ISSN: 2167-0277

Journal of Sleep Disorders & Therapy
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Case Report

Abnormal Endocrine and Behavioural Sleep Markers in a Child with Williams Syndrome and Siblings

Dagmara Dimitrio1,2*, Anna Sniecinska3 and Ray K Iles4
1Department of Psychology and Human Development, Institute of Education, London, United Kingdom, UK
2School of Health and Social Science, Middlesex University, London, UK
3Faculty of Health, Social Care and Education, Anglia Ruskin University, Chelmsford, UK
4Eric Leonard Kruse Foundation for Health Research, Scotland
Corresponding Author : Dagmara Dimitriou, PhD
Department of Psychology and Human Development
Institute of Education, London, United Kingdom
Tel: +44 (0)20 7612 6229
Fax: +44 (0)20 7612 6304
E-mail: [email protected]
Received October 29, 2012; Accepted February 23, 2013; Published February 28, 2013
Citation: Dimitriou D, Sniecinska A, Iles RK (2013) Abnormal Endocrine and Behavioural Sleep Markers in a Child with Williams Syndrome and Siblings. J Sleep Disord Ther 2:108. doi:10.4172/2167-0277.1000108
Copyright: © 2013 Dimitriou D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: Sleep is critical for optimal child development. However, the role of different variables that
influence sleep functioning is still debatable. Children with developmental disorders such as Williams syndrome
(WS) suffer from sleep problems throughout their childhood. Little is known about sleep patterns of their siblings.
Methods: Triplets, one of whom has WS and four typically developing (TD) children matched on age (7.8 years
old) and gender participated in the study. Sleep was measured using parental sleep questionnaire and actigraphy.
Salivary melatonin and cortisol were measured at three time points during the day.
Results: Abnormal sleep patterns, levels of melatonin and cortisol were found in a child with WS and her
siblings.
Conclusion: These findings indicate that siblings of children with developmental disorders may also exhibit
similar sleep problems. Use of multi-level examination should be adapted by paediatricians to devise sleep
management strategies for such children and their families.

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