alexa About a Gastric Neuroendocrine Tumor Presenting as Polymyalgia Rheumatica and Macrocytic Anemia
ISSN: 2165-7920

Journal of Clinical Case Reports
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Case Report

About a Gastric Neuroendocrine Tumor Presenting as Polymyalgia Rheumatica and Macrocytic Anemia

Ciro Manzo*

Asl Napoli 3 Sud, Mariano Lauro hospital, Sant’Agnello, Naples, Italy

*Corresponding Author:
Ciro Manzo
Asl Napoli 3 Sud
Mariano Lauro hospital
Sant’Agnello, Naples, Italy
Tel: 40632061439902
E-mail: [email protected]

Received March 31, 2016; Accepted May 12, 2016; Published May 17, 2016

Citation: Manzo C (2016) About a Gastric Neuroendocrine Tumor Presenting as Polymyalgia Rheumatica and Macrocytic Anemia. J Clin Case Rep 6:784. doi:10.4172/2165-7920.1000784

Copyright: © 2016 Manzo C. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Polymyalgia rheumatica (PMR) is considered the commonest rheumatic inflammatory disease in the elderly. The relationship between PMR and cancer is still complex. The possibility that PMR can represent a paraneoplastic syndrome has been more and more descripted. A lack of response to corticosteroid therapy is considered the principal element for looking for a paraneoplastic syndrome. Gastric gastrin-secreting tumor represents an uncommon gastric tumor, especially in the elderly. We describe the clinical case of a patient in which PMR associated with a mild macrocytic anemia was the key for diagnosis of a gastric gastrin-secreting tumor. Endoscopic removal of neoplastic polyps and an octreotide long-lasting therapy caused the prompt and permanent disappearance of PMR manifestations. According to our knowledge, it’s the first time that this association is descripted.


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