alexa Acute Clostridium Difficile Infection in two Polish Pregnant Women with Premature Rupture of Membranes | OMICS International | Abstract
ISSN: 2161-0703

Journal of Medical Microbiology & Diagnosis
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Case Report

Acute Clostridium Difficile Infection in two Polish Pregnant Women with Premature Rupture of Membranes

Joanna Skret- Magierlo1,2*, Edyta Barnas2, Renata Ras1, Krzysztof Gutkowski3, Leszek Juszczyk4, Alex van Belkum5, Hanna Pituch6and Andrzej Skret1

1Clinical Department of Obstetrics and Gynecology, Rzeszów State Hospital, Rzeszów, Poland

2Institute of Obstetrics and Emergency Medicine, University of Rzeszów, Poland

3Clinical Department of Gastroenterology and Hepatology, Rzeszów State Hospital, Rzeszów, Poland

4Obstetrics and Gynecology Hospital „Ujastek”, Crakow, Poland

5bioMérieux R&D Microbiology, La Balme Les Grottes, France

6Department of Medical Microbiology, Medical University of Warsaw, Poland

*Corresponding Author:
Joanna Skret- Magierlo
Clinical Department of Obstetrics and Gynecology
Rzeszów State Hospital, Rzeszów, Poland
Tel: 48 17 872 10 00
E-mail: [email protected]

Received date: June 15, 2015 Accepted date: August 18, 2015 Published date: August 21, 2015

Citation: Skret- Magierlo J, Barnas E, Ras R, Gutkowski K, Juszczyk L, et al. (2015) Acute Clostridium Difficile Infection in two Polish Pregnant Women with Premature Rupture of Membranes. J Medical Microbiol Diagnosis S5:003. doi:10.4172/2161-0703.S5-003

Copyright: © 2015 Skret- Magierlo J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


We present two cases of acute Clostridium difficile infection (CDI) during pregnancy in Poland. Both patients were hospitalized due to premature rupture of membranes at 15 and 28 weeks of gestation and had antibiotic prophylaxy and therapy. The first patient was discharged on day 18 after the start of the infection but the second patient died after 4 days of hospitalization. Our data and a literature review show that extensive antibiotic usage in such patients may predispose to CDI despite a current lack of detailed studies.BV and health state will provide the depth insight in the etiology of BV.


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