alexa Acute Generalized Exanthematous Pustulosis in a 51-Year-Old Patient under Etanercept Treatment for Psoriasis
ISSN: 2329-6887

Journal of Pharmacovigilance
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Case Report

Acute Generalized Exanthematous Pustulosis in a 51-Year-Old Patient under Etanercept Treatment for Psoriasis

Luciana Mabel Ferreira Vasconcelos1, Fabricia Martins Teixeira2, Eudiana Vale Francelino3, Thereza Lucia Prata Almeida4,
Larissa Bomfim Chagas4, Jose Telmo Valença Jr5 and Aparecida Tiemi Nagao-Dias6*
1Posgraduation Program of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Ceara (UFC), Brazil
2Central Public Health Laboratory (LACEN), Ceara, Brazil
3Faculty of Pharmacy, Pharmacovigilance Center of Ceara, UFC, Brazil
4Department of Dermatology, Hospital Universitário Walter Cantídio, UFC, Brazil
5Faculty of Medicine, Department of Pathology, UFC, Brazil
6Faculty of Pharmacy, Department of Clinical Analysis and Toxicology, UFC, Brazil
Corresponding Author : Aparecida Tiemi Nagao-Dias
Faculty of Pharmacy, Department of Clinical Analysis and Toxicology
Federal University of Ceara, Rua Capitao Francisco Pedro
1210, CEP 60430-370, Fortaleza, Ceará, Brazil
Tel: 55-85-3366-8270
Fax: 55-85-3366-8292
E-mail: tiemindi@yahoo.com.br
Received November 06, 2013; Accepted February 04, 2014; Published February 11, 2014
Citation: Vasconcelos LMF, Teixeira FM, Francelino EV, Almeida TLP, Chagas LB, et al. (2014) Acute Generalized Exanthematous Pustulosis in a 51-Year-Old Patient under Etanercept Treatment for Psoriasis. J Pharmacovigilance 2:120. doi: 10.4172/2329-6887.1000120
Copyright: © 2014 Vasconcelos LMF, et al., This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Related article at
DownloadPubmed DownloadScholar Google

Abstract

Acute generalized exanthematous pustulosis (AGEP) is a cutaneous reaction mostly related to drug, which is characterized by a rapid appearance of fever, erythema, sterile pustules and neutrophilia. We report a 51-year-old female patient who had taken etanercept 50 mg/week for treatment of psoriasis. In the third month of pharmacotherapy, she interrupted the treatment on her own, and consequently, the lesions reappeared. When the drug was reintroduced, it was associated with prednisone 40 mg/day during 5 days. After this period, multiple erythematous and edematous lesions appeared with small non-follicular pustules. Oral corticosteroid was administered and a progressive and complete improvement was achieved. Histopathological findings revealed AGEP. Bacterioscopy of the pustules proved negative. The patient obtained the score 12 according to the EuroSCAR study group, which indicated a definitive diagnosis of AGEP. The criteria for diagnosis were based on morphology, course and histology of the skin reaction. The association between Etanercept and AGEP is an uncommon finding in the literature.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

agriaquaculture@omicsonline.com

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

biochemjournals@omicsonline.com

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

business@omicsonline.com

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

chemistryjournals@omicsonline.com

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

clinicaljournals@omicsonline.com

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

engineeringjournals@omicsonline.com

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

nutritionjournals@omicsonline.com

1-702-714-7001Extn: 9042

General Science

Andrea Jason

generalscience@omicsonline.com

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

geneticsmolbio@omicsonline.com

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

immunomicrobiol@omicsonline.com

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

materialsci@omicsonline.com

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

nursinghealthcare@omicsonline.com

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

medicaljournals@omicsonline.com

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

neuropsychology@omicsonline.com

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

pharmajournals@omicsonline.com

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

social_politicalsci@omicsonline.com

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords