alexa Acute Imidacloprid Poisoning Caused Prolong Depression of Butyrylcholinesterase | OMICS International | Abstract
ISSN: 2161-0495

Journal of Clinical Toxicology
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Case Report

Acute Imidacloprid Poisoning Caused Prolong Depression of Butyrylcholinesterase

Chih-Chuan Lin1*, Jen-Hou Li2 and Te-Fa Chiu1

1Department of Emergency Medicine, Chang Gung Memorial Hospital and Chang Gung University, Linko, Taiwan

2Residue Control Division, Taiwan Agricultural Chemical and Toxic Substances Research Institute, Taiwan

*Corresponding Author:
Chih-Chuan Lin
Department of Emergency Medicine
Chang Gung Memorial Hospital and
Chang Gung University, Linko, Taiwan
Tel: +886-3-3281200, ext 3347
E-mail: [email protected]

Received date: June 26, 2015 Accepted date: August 21, 2015 Published date: August 25, 2015

Citation: Lin CC, Li HJ, Chiu TF (2015) Acute Imidacloprid Poisoning Caused Prolong Depression of Butyrylcholinesterase. J Clin Toxicol 5:261. doi:10.4172/2161-0495.1000261

Copyright: © 2015 Lin CC. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Background: Imidacloprid is currently one of the most widely used insecticides in the world. To the best of our knowledge, there is no study showing that imidacloprid decreases the butyrylcholinesterase activity in humans. However, here we present a case of suicide attempt by imidacloprid with prolong depression of butyrylcholinesterase activity.

Case Report: This is an observational case report of a patient attempted suicide by unknown pesticides. Pralidoxime and atropine were administrated under the impression of organophosphate poisoning based on the depression of butyrylcholinesterase activity. However, due to the patient’s atypical presentation for organophosphate poisoning, pralidoxime was stopped and patient’s condition was getting stable under supportive treatment. Patient’s urine sample revealed the presence of imidacloprid but not other pesticides. Serial false depressions of butyrylcholinesterase activity were also detected in our patient.


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