alexa Acute Ophthalmoplegia without Ataxia: A Case Report
ISSN: 2165-7920

Journal of Clinical Case Reports
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Case Report

Acute Ophthalmoplegia without Ataxia: A Case Report

Edvard Ehler1,2, Leona Formanova1,2, Alena Melekova1,2, Petra Mandysova1,2 and Martin Valis3*

1Department of Neurology, Pardubice Regional Hospital, Pardubice, Czech Republic

2Faculty of Health Studies, University of Pardubice, Pardubice, Czech Republic

3Department of Neurology, Charles University and University Hospital, Hradec Kralove, Czech Republic

*Corresponding Author:
Martin Valis
Department of Neurology
Charles University and University Hospital
Sokolska 581, 500 05
Hradec Kralove, Czech Republic
Tel: +420 495 835 233
Fax: +420 495 835 200

Rec date: Mar 27, 2016; Acc date: May 13, 2016; Pub date: May 16, 2016

Citation: Ehler E, Formanova L, Melekova A, Mandysova P, Valis M (2016) Acute Ophthalmoplegia without Ataxia: A Case Report. J Clin Case Rep 6:791. doi:10.4172/2165-7920.1000791

Copyright: © 2016 Ehler E, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Background: Miller Fisher syndrome is a well-known disorder that belongs to a group of conditions with a high level of antibodies against ganglioside GQ1b. It is characterized by acute onset of ataxia, areflexia, and ophthalmoplegia. In cases of acute-onset ophthalmoplegia without ataxia, the diagnosis is more difficult; therefore, it is frequently delayed. Case Report: We report one such case of rapid onset of internal ophthalmoplegia, followed by external ophthalmoplegia. The diagnostic process was challenging, but eventually, a high level of antibodies against GQ1b confirmed the diagnosis. Because the clinical and electrophysiological findings were limited only to the presence of anti-GQ1b antibodies, a combination with a generalized form of Guillain-Barre syndrome could be excluded. Conclusion: Consequently, the patient was not treated with immunotherapy. At 4 months, the patient had made a good recovery.


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