alexa Acyclovir Crystalluria: A Rare Secondary Effect of a Common Drug
ISSN: 2161-0665

Pediatrics & Therapeutics
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Case Report

Acyclovir Crystalluria: A Rare Secondary Effect of a Common Drug

Claudia Sánchez-Villares Lorenzo*, Sheila De Pedro, Ana Isabel Benito and Carla Criado

Department of Pediatrics, University Hospital of Salamanca, Spain

*Corresponding Author:
Claudia Sánchez-Villares Lorenzo
Department of Pediatrics
University Hospital of Salamanca, Spain
Tel: 34-605-57-64-10
E-mail: [email protected]

Received date April 19, 2016; Accepted date May 19, 2016; Published date May 23, 2016

Citation: Lorenzo CS, Pedro SD, Benito AI, Criado C (2016) Acyclovir Crystalluria: A Rare Secondary Effect of a Common Drug. Pediatr Ther 6:287. doi:10.4172/2161-0665.1000287

Copyright: ©2016 Lorenzo CS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.



Acyclovir is a highly active antiviral drug that acts against the herpes simplex virus (HSV). Among its secondary effects, we can observe rare cases of crystalluria, which can be associated or not associated to renal failure. We present the case of a healthy lactating 13-month-old baby girl with gingivostomatitis, who 48 hours after the start of treatment with this drug showed a change in the color of her urine, which was associated with the appearance of crystals in the sediment. This finding was associated with the prescription of Acyclovir, because it has been described in the literature, and no other ascribable causes could be found. Crystalluria is a rare adverse effect that has been reported generally in adult immunosuppressed patients. We have only been able to find one case that could be compared to ours, in an immunocompetent pediatric patient in which a momentary treatment was implemented to treat a herpetic infection.


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version