Reach Us +44-1202-068036
Addiction and Autism: A Remarkable Comorbidity? | OMICS International | Abstract
ISSN: 2329-6488

Journal of Alcoholism & Drug Dependence
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Addiction and Autism: A Remarkable Comorbidity?

Patricia JM van Wijngaarden-Cremers1,2*, Wim Van den Brink MD3 and Rutger Jan van der Gaag2

1Dimence Mental Health – Deventer, The Netherlands

2Radboud University Medical Centre Nijmegen–Karakter University Centre Child & Adolescent Psychiatry, The Netherlands

3Academic Medical Centre Amsterdam (AMC) & Amsterdam Institute for Addiction Research (ARIAR), The Netherlands

*Corresponding Author:
Patricia van Wijngaarden-Cremers
Radboud University Medical Centre Nijmegen – Karakter University
Centre Child & Adolescent Psychiatry, The Netherlands
Tel: +31-24-361-11
E-mail: [email protected]

Received date: May 05, 2014; Accepted date: July 20, 2014; Published date: July 25, 2014

Citation: Wijngaarden-Cremers PJM, Brink WV, Gaag RJ (2014) Addiction and Autism: A Remarkable Comorbidity?. J Alcohol Drug Depend 2:170. doi:10.4172/2329-6488.1000170

Copyright: © 2014 Wijngaarden-Cremers PJM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Objective: Autism Spectrum Disorders (ASD) are well known for high prevalence’s of comorbid conditions especially anxiety, obsessions, depression and challenging behaviours. In this article we will consider the evidence for an eventual comorbidity between ASD and Addiction (Substance Use Disorders (SUD) and explore the possible underlying explanations.

Methods: A literature study on similarities between Addiction and ASD (at a phenotypical and neurobiological level) as well as a case note review on a year cohort of 200 consecutive admissions in an adult addiction psychiatry unit was studied here.

Results: In our pilot-survey 8 (men) on 118 patients were diagnosed with autism spectrum disorder. This is substantially higher than in the general population (1%) but in line with other European studies.

Autism spectrum disorders and addiction can both be perceived as developmental disorders in which a genetic predisposition and vulnerability interact with environmental factors. They can be induced by early stress thus affecting the proper functioning of the cortico-striatal dopaminergic regulation systems (and also the HPA axis). There is growing evidence that ASD and SUD share developmental dysregulations of the limbic and sensorimotor cortico-striatal regulations loops.

Conclusions: There are clear indications that a possible comorbidity of substance abuse disorder should be considered in cases of individuals with autism spectrum disorders. This finding is important for clinicians to take into account in assessing patients with addiction problems or ASD.


Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2019-20
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri and Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

ankara escort

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

pendik escort

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2019 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version