Adult Human Ocular Volume: Scaling to Body Size and Composition
- Corresponding Author:
- Steven B Heymsfield
Pennington Biomedical Research Center
6400 Perkins Rd., Baton Rouge, LA 70808, USA
E-mail: [email protected]
Received Date: August 06, 2016; Accepted Date: August 24, 2016; Published Date: August 30, 2016
Citation: Heymsfield SB, Gonzalez MC, Thomas D, Murray K, Jia G, et al. (2016) Adult Human Ocular Volume: Scaling to Body Size and Composition. Anat Physiol 6:239. doi:10.4172/2161-0940.1000239
Copyright: © 2016 Heymsfield SB, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Objectives: Little is currently known on how human ocular volume (OV) relates to body size or composition across adult men and women. This gap was filled in an exploratory study on the path to developing anthropological and physiological models by measuring OV in young healthy adults and related brain, head, and body mass along with major body components. Methods: Thirty-six men and 44 women, ages 20-35 yrs, were evaluated with magnetic resonance imaging and dual-energy X-ray absorptiometry that provided estimates of OV, brain, head, fat, lean soft tissue (LST), and bone mineral mass. Associations between OV and other components were evaluated first followed by development of allometric models relating OV and other components to body size as defined by stature. Results: Mean OV was non-significantly larger in men (X ± SD; 6.35 ± 0.69 cm3) than in women (6.26 ± 0.53 cm3; P=NS), although OV in women was significantly larger relative to brain and head mass than in men (both p<0.001). While larger body components (e.g., LST) scaled to height with powers as expected from previous studies, these associations for OV were weak or non-significant. Our findings are consistent with a systematic review of earlier autopsy, surgical, and imaging OV studies. Conclusions: Unlike most other lean tissues and organs, the absolute eye volume is largely independent of a person’s sex and body size or composition. As a small anatomic body component, the adult human eye appears to function within relatively narrow dimensional constraints. Future larger sample studies are needed to explore age and racial/ethnic differences in OV.