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Adult T Cell Leukemia/Lymphoma in a 56 years Old Indian Male with History of Miliary Kochs on Anti-Tubercular Therapy | OMICS International | Abstract
ISSN: 2471-8556

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Case Report

Adult T Cell Leukemia/Lymphoma in a 56 years Old Indian Male with History of Miliary Kochs on Anti-Tubercular Therapy

Neeraj Kumar Tulara*
Dr LH Hiranandani Hospital, Hillside Avenue, Hiranandani Gardens, Powai, Mumbai, India
*Corresponding Author : Neeraj Kumar Tulara
Dr LH Hiranandani Hospital, Hillside Avenue
Hiranandani Gardens, Powai, Mumbai 400076, India
Tel: +91-9833552955
E-mail: [email protected]
Received: February 24, 2016; Accepted: March 07, 2016; Published: March 10, 2016
Citation: Tulara NK (2016) Adult T Cell Leukemia/Lymphoma in a 56 years Old Indian Male with History of Miliary Koch’s on Anti-Tubercular Therapy. Oncol Cancer Case Rep 2:110. doi:10.4172/occrs.1000110
Copyright: © 2016 Tulara NK. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Adult T-cell leukemia/lymphoma (ATLL) is a rare T lymph proliferative disorder which is etiologically linked with human T-cell lymphotropic virus type-1 (HTLV-1). HTLV-1 is endemic in Japan, Caribbean and Africa. The highest incidence of ATLL is in Japan although sporadic cases have been reported elsewhere in the world. We describe a case of ATLL where a 56-year-old Indian male was referred to our hospital for increasing swelling on the left side of neck and thigh since last one month. Clinical examination revealed tender left cervical mass (150 mm by 90 mm) that was fixed, warm and slightly erythematous. A subcutaneous mass (40 mm by 35 mm) on the left thigh was non-tender and without erythema. Histopathological examination of the neck and thigh mass showed mixtures of intermediate and large atypical tumor cells. Immunohistochemical staining was positive for CD3, CD4 and CD8 and negative for CD29 and CD 79a, results that were consistent with T-cell lymphoma. Testing for antibody to human T-cell leukemia virus type 1 (HTLV-1) was positive.

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