After HCV Eradication with SovaldiÃÂ®, Can Herbs Regenerate Damaged Liver, Minimize Side Effects and Reduce the Bill?
Nada M Mostafa and Abdel Nasser Singab*
Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt
- *Corresponding Author:
- Singab AN
Department of Pharmacognosy
Faculty of Pharmacy, Ain Shams University, 11566, Cairo, Egypt
E-mail: [email protected] (or) [email protected]
Received date: June 16, 2016; Accepted date: June 30, 2016; Published date: July 04, 2016
Citation: Mostafa NM, Singab AN (2016) After HCV Eradication with Sovaldi®, Can Herbs Regenerate Damaged Liver, Minimize Side Effects and Reduce the Bill? Med Aromat Plants 5:257. doi:10.4172/2167-0412.1000257
Copyright: © 2016 Mostafa NM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Objective: Hepatitis C virus is a major health burden. It has infected millions of people worldwide with the highest prevalence in Egypt. Sofosbuvir (Sovaldi®) has been recently approved for treating chronic hepatitis C virus infections. Herbal medicine has been searched for centuries for the remedy of liver diseases.
Key findings: Plants contain phytochemicals that proved to demonstrate hepatoprotective activity in vitro in various hepatotoxic models. Herbal drugs also proved efficacy in many clinical trials in reducing the viral load and improving the clinical manifestations in patients suffering hepatitis C virus.
Conclusions: A hypothesis is postulated for the possibility of the use of a herbal mixture of plants, which are known for their hepatoprotective activity, in a combination therapy with directly acting antiviral drugs such as Sovaldi® to help regenerate the liver, improve the clinical condition and reduce both the cost and side effects for hepatitis C virus patients.