Agnucaston and Clomiphen Citrate in Infertile Patients with Polycystic Ovaries
|Department of Obstetrics and Gynecology, IVF Division, Benha Faculty of Medicine, Egypt|
|*Corresponding Author :||Dr Mostafa Abdulla Elsayed, PhD
Department of Obstetrics and Gynecology
IVF Division, Benha Faculty of Medicine
Street no 3. New Villal, Benha -Qalubia-Egypt
E-mail: [email protected]
|Received July 13, 2013; Accepted August 05, 2013; Published August 07, 2013|
|Citation: Elsayed MA (2013) Agnucaston and Clomiphen Citrate in Infertile Patients with Polycystic Ovaries. J Fertil In Vitro IVF Worldw Reprod Med Genet Stem Cell Biol 1:108. doi:10.4172/2375-4508.1000108|
|Copyright: © 2013 Elsayed MA. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
Objectives: To study the effect of agnucaston with clomiphen citrate in infertile patients with polycystic ovaries.
Study type: Controlled trial.
Materials and Methods: One hundred infertile cases with polycystic ovaries randomized into two groups fifty (50) cases received clomiphen citrate 50 mg from second day of menstruation two tablets per day for 5 days in addition with agnucaston (agnus castus, Binoreca) two tablets per day from the first day of menstruation for 14 days the other group received only clomiphen citrate 50 mg two tablets per day from second day for 5 days.
Results: Group 1(combined agnucaston with clomiphen citrate the pregnancy rate is 30 out of 50 (60%) while the second group the (clomiphen only group) pregnancy rate is 15 out of 50 (30%).