Airway Hyperresponsiveness and Inflammation: Causation, Correlation, or No Relation?
- *Corresponding Author:
John F. Alcorn
Department of Pediatrics Children’s Hospital of Pittsburgh of UPMC
One Children’s Hospital Dr., 4401 Penn Ave
9127 Rangos, Pittsburgh, PA 15224, USA
E-mail: [email protected]
Received Date: November 14, 2011; Accepted Date: January 22, 2012; Published Date: January 26, 2012
Citation: Janssen-Heininger YMW, Irvin CG, Scheller EV, Brown AL, Kolls JK, et al. (2012) Airway Hyperresponsiveness and Inflammation: Causation, Correlation, or No Relation? J Aller Ther S1:008. doi: 10.4172/2155-6121.S1-008
Copyright: © 2012 Janssen-Heininger YMW, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Asthma represents a growing problem in the developing world, affecting millions of children and adults. Features of the disease are reversible airflow obstruction, airway hyperresponsiveness and airway inflammation leading to tissue damage and remodeling. Many studies have attempted to address whether inflammation and airway hyperresponsiveness are mechanistically linked.