alexa Alcohol Intake Improves Adherence of Pregabalin and Tramadol/Acetaminophen to RA and OA Patients
ISSN: 2161-1149

Rheumatology: Current Research
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Research Article

Alcohol Intake Improves Adherence of Pregabalin and Tramadol/Acetaminophen to RA and OA Patients

Wataru Shimada1, Yasunori Itoh1, Osamu Matsuo2 and Hiraku Kikuchi1*

1Department of Orthopaedic Surgery, Sakai Hospital, Kinki University Faculty of Medicine, Sakai, 590-0132, Japan

2Kinki University Faculty of Medicine, Osakasayama, 589-8511, Japan

*Corresponding Author:
Prof. Hiraku Kikuchi
Department of Orthopedics, Sakai Hospital
2-7-1 Harayamadai, Minami-ku, Sakai 590-0132, Japan
Tel: +81-72-299-1120
Fax: +81-72-298-6691
E-mail: [email protected]

Received Date: August 23, 2014; Accepted Date: September 23, 2014; Published Date: September 30, 2014

Citation: Shimada W, Itoh Y, Matsuo O, Kikuchi H (2014) Alcohol Intake Improves Adherence of Pregabalin and Tramadol/Acetaminophen to RA and OA Patients. Rheumatology (Sunnyvale) S5:005. doi: 10.4172/2161-1149.S5-005

Copyright: © 2014 Shimada, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Clinical managements of chronic pain in rheumatoid arthritis (RA) and osteoarthritis (OA) require deep
understanding of patients. Since medication is mostly set under the guidelines of RA and OA to control of pain, but
personal characteristics is not so much paid attention in terms of preferences. In the present study, alcohol
preference was analyzed in the patients prescribed pregabalin and tramadol/acetaminophen in our hospital. All
consecutive patients were requested to write up the medical questionnaire sheet before medical examination. The
responses to this sheet are completely subjective. The close relation between habitual alcohol drinking and
adherence of analgesics was observed in terms of adherence of pregabalin and tramadol/acetaminophen. That is, in
OA patients, alcohol drinkers showed good adherence to pregabalin and also tramadol/acetaminophen. However, in
RA patients, alcohol drinkers showed higher ratio to good adherence, but there was no significance between alcohol
drinkers and non-alcohol drinkers. When total patients were analyzed, alcohol drinkers showed significantly higher
adherence with pregabalin and also tramadol/acetaminophen. Therefore, it is recommended that precise personal
preference had better to be taken in medical examination before prescription of pregabalin and tramadol/
acetaminophen in RA and OA patients.


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