alexa Alcoholism: Common and Oxidative Damage Biomarkers
ISSN: 2161-0495

Journal of Clinical Toxicology
Open Access

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Review Article

Alcoholism: Common and Oxidative Damage Biomarkers

Saé Muñiz-Hernández1, Jesús B Velázquez-Fernández2, José Díaz-Chávez1, Rosa C López-Sánchez3, José A Hernández3 and Adela Rendón-Ramírez4*

1Subdirección de Investigación Básica, Instituto Nacional de Cancerología, Secretaría de Salud Mexico (SS), USA

2Laboratorio de Bioquímica Toxicológica, Posgrado en Ciencias Biológico Agropecuarias y Pesqueras, Universidad Autónoma de Nayarit, USA

3Tecnológico de Monterrey, Escuela de Medicina y Ciencias de la Salud, USA

4Unidad de Biofísica (Centro Mixto CSIC, UPV/EHU), Universidad del País Vasco, Spain

*Corresponding Author:
Adela Rendón Ramírez
Unidad de Biofísica (CSIC-UPV/EHU) - Fundación Biofísica Bizkaia
Aptdo 644, 48080 Bilbao, España, Spain
Tel: +34647 496 436
E-mail: [email protected]

Received date: March 03, 2014; Accepted date: April 28, 2014; Published date: April 30, 2014

Citation: Muñiz-Hernández S, Velázquez-Fernández JB, Díaz-Chávez J, López-Sánchez RC, Hernández JA, et al. (2014) Alcoholism: Common and Oxidative Damage Biomarkers . J Clin Toxicol S7:006. doi: 10.4172/2161-0495.S7-006

Copyright: © 2014 Saé Muñiz-Hernández, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

For many years it has been assumed that moderate alcohol intake might provide health benefits to humans, while alcohol abuse generally produces some systemic complications, even when physical and mental dependence on alcohol has not developed. Many studies have focused on distinct molecules that might serve as useful early or late biomarkers in individuals that consume important amounts of alcohol. Indeed, the diversity of molecules postulated as biomarkers is quite wide and this is the direct reflection of the broad range of mechanisms involved in the impact that alcohol has on human health, either as a result of acute or chronic intake, the latter being a cause death. In this review, we have considered most of the molecules that have been followed-up in individuals who drink large amounts of alcohol, as well as some of those that have been less intensely studied, and we present a pair of oxidative biomarkers that could be used to evaluate early stage alcoholism.

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