An Assessment of Antioxidant and Antiproliferative Activities of Super Grain Quinoa
CUNY School of Public Health, NY 10035, USA
- *Corresponding Author:
- Sikha Bhaduri
CUNY School of Public Health
NY 10035, USA
Tel: +1 212 396 7789
E-mail: [email protected]
Received Date: December 02, 2015; Accepted Date: December 29, 2015; Published Date: January 08, 2016
Citation: Bhaduri S (2016) An Assessment of Antioxidant and Antiproliferative Activities of Super Grain Quinoa. J Food Process Technol 7:549.doi:10.4172/2157-7110.1000549
Copyright: © 2016 Bhaduri S. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Quinoa is known to be an excellent source of natural antioxidants and therefore the extract of quinoa seed was considered to have a significant anti-inflammatory activity. Two different varieties of quinoa seeds and six different solvents hexane, acetone, methanol, ethanol, ethyl acetate and water were used as solvent for extraction in the present study. Extracts from water, methanol and ethanol showed significant antioxidant and phytochemical activities. Water extract showed highest Phenol content (89.73 ± 1.74), antioxidant activity (1586 ± 41.42) and DPPH scavenging capacities (82.71 ± 0.03) compared to other solvents used for extraction. IC50 value for percentage DPPH scavenging capacities by water extract was 14.71 ± 0.02, compared to ascorbic acid (7.15 ± 0.13), which is a control. All extracts exhibit significantly high levels of flavonoid content. Ethyl acetate extract represented highest (88.41 ± 0.37) NO scavenging capacity. Lowest IC50 value (52.58 ± 0.14) for NO scavenging capacity was identified for ethanol extract compared to control (24.19 ± 3.53). Ascorbic acid used as control in both DPPH and Nitric oxide scavenging capacities measurement. Quinoa seed extracts from all six solvents found to have antimicrobial activities towards gram positive bacteria but not towards all gram negative bacteria. All extracts showed significant anti proliferative activities towards P 116 cells.