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Research Article
An Efficient Synthesis of Some New Azaspirocycloalkane Derivatives from 1-anilinocycloalkanecarboxamide
Mounir AA Mohamed1, Hassan M Moustafa1 and Mahmoud Abd El Aleem Ali El-Remaily1,2*
1Chemistry Department, Faculty of Science, Sohag University, 82524 Sohag, Egypt
2Department of Organic Chemistry, Faculty of Science, Granada University, Granada, E-18071, Spain
- Corresponding Author:
- Mahmoud Abd El Aleem Ali El-Remaily
Department of Organic Chemistry, Faculty of Science
Granada University, Granada, E-18071, Spain
Tel: +201008036348
Fax: +209360115982524
E-mail: [email protected]
Received date: May 16, 2014; Accepted date: May 28, 2014; Published date: June 05, 2014
Citation: Mohamed MAA, Moustafa HM, Ali El-Remaily MAEA (2014) An Efficient Synthesis of Some New Azaspirocycloalkane Derivatives from 1-anilinocycloalkanecarboxamide. Chem Sci J 5:083. doi:10.4172/2150-3494.1000083
Copyright: © 2014 Mohamed MAA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
1-anilinocyclohexanecarboxamides 2a-c were found to be a versatile precursors for the synthesis of five-, six- and seven-membered ring spiroheterocycles compounds 3-14. A general high yielding protocol for the synthesis of many functionalized spiro heterocyclic systems was presented.
