An Overview of Immunologic Adjuvants - A ReviewAiyer Harini P*, Ashok Kumar HG, Gupta Praveen Kumar and Shivakumar Neeta
Department of Biotechnology, R. V College of Engineering, Bangalore-59, India
- *Corresponding Author:
- Aiyer Harini P
Department of Biotechnology
R.V College of Engineering
E-mail: [email protected]
Received date: December 19, 2012; Accepted date: January 27, 2013; Published date: January 29, 2013
Citation: Aiyer Harini P, Ashok Kumar HG, Praveen Kumar G, Shivakumar N (2013) An Overview of Immunologic Adjuvants - A Review. J Vaccines Vaccin 4:167. doi: 10.4172/2157-7560.1000167
Copyright: © 2013 Aiyer Harini P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
With the onset of antigen production using biosynthetic and rDNA techniques, the need to administer adjuvants
along with vaccines has increased remarkably. This search for accompanying adjuvants has resulted in a multitude of molecules from mineral salts to bacterial polysaccharides and Immuno stimulatory complexes that range considerably in efficacy. Moreover, the adjuvant molecule is specific to its antigen molecule and hence has to be tailored suitably to maximise efficacy and safety, maintaining the cost at a minimum. This paper explores the characteristics of these molecules, their mode of action and the advancements in the field.