An Unusual Case of Multiple Primary Carcinomas: Breast Cancer and Rectal Adenocarcinoma in a Single Patient: Report of a Case and Review of the LiteratureAkasbi Y1*, Arifi S1, Najib R1, Hammas N2, Amarti A2 and Mellas N1
- *Corresponding Author:
- Akasbi Yousra
Medical Oncology Department
Hassan II University Hospital
E-mail: [email protected]
Received date: November 10, 2015; Accepted date: December 26, 2015; Published date: December 30, 2015
Citation: Akasbi Y, Arifi S, Najib R, Hammas N, Amarti A, et al. (2015) An Unusual Case of Multiple Primary Carcinomas: Breast Cancer and Rectal Adenocarcinoma in a Single Patient: Report of a Case and Review of the Literature. Arch Surg Oncol 1:107. doi:10.4172/2471-2671.1000107
Copyright: © Akasbi Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Introduction: The incidence of multiple primary malignant neoplasms (MPMN) increases with age. While they are nowadays encountered more frequently, the phenomenon is still considered to be rare. Our case represent a rare association between breast and rectal cancer. Multiplicity of primary malignancies itself does not necessarily indicate a poor prognosis as long as adequate diagnosis and management are performed.
Case presentation: We report a case of a Moroccan female, aged 46 years old, who was diagnosed with both a breast cancer metachronous and rectal adenocarcinoma within an eleven years period. The literature on multiple primary malignancies in a single patient is reviewed and the data are summarized.
Conclusion: From this rare case report and a review of the literature, it would appear that individuals who developed one malignancy might be at greater risk of developing a second. The occurrence of multiple primary malignant neoplasms in our case may be explained by microsatellite instability, and increased surveillance. But there is no genetic predisposition.