Analysis of Related Factors of Behavioral and Psychiatric Symptoms in Vascular Dementia
HF Chen, XL Pan, HM Kong, YM Fu, CC Hu, JW Wang and HJ Shao*
Department of Neurology, Jinhua Hospital of Zhejiang University, Jinhua, Zhejiang, China
- *Corresponding Author:
- HJ Shao
Department of Neurology
Jinhua Hospital of Zhejiang University
Jinhua 321000, Zhejiang, China
E-mail: [email protected]
Received Date: July 10, 2015 Accepted Date: October 19, 2015 Published Date: October 25, 2015
Citation: Chen HF, Pan XL, Kong HM, Fu YM, Hu CC, et al. (2015) Analysis of Related Factors of Behavioral and Psychiatric Symptoms in Vascular Dementia. J Psychiatry 18:338 doi:10.4172/2378-5756.1000338
Copyright: © 2015 Chen HF, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Objective: The aims of this study were to investigate the relationship between behavioral and psychological symptoms and cognitive disturbances, ages, educations of patients and investigate the correlations among Neuropsychiatric inventory (NPI) items in patients with vascular dementia (VaD). Methods: NPI and Mini-Mental State Examination (MMSE) were used to assess the behavioral and psychological symptoms in 120 cases with VaD and 61 cases healthy elders as control group.
Results: The score about delusion, hallucination, agitation, dysphoria, apathy, irritability, aberrant motor and appetite/eating change in the NPI list were significantly increased compared with control group (P<0.05), in which the highest score in turn were dysphoria, apathy and irritability. Among the 8 items in the NPI list, delusion, apathy and aberrant motor were significantly corelated with cognitive disorder (P<0.05), and abnormal behavior was corelated with ages and educations. Besides, NPI factors analysis showed there were three behavioral sub-syndromes, such as psychosis, mood disorder and behavioral disturbance.
Conclusions: Behavioral and psychological symptoms were common in VaD patients, and the frequency and severity of behavioral and psychological symptoms were corelated with cognitive disturbances, ages, and education status at different degrees.