alexa Angiosuppresive activity of Leucas aspera (Willd) Linn. using Chicken Chorioallantoic Membrane (CAM) assay
ISSN ONLINE(2319-8753)PRINT(2347-6710)

International Journal of Innovative Research in Science, Engineering and Technology
Open Access

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Research Article

Angiosuppresive activity of Leucas aspera (Willd) Linn. using Chicken Chorioallantoic Membrane (CAM) assay

Sri Devi M1, Vinothini K1, Veronica Shalini2, Krishnamoorthy Masilamani3, Dharini Sivakumar4 and Arjun Pandian4
  1. PG Student, Department of Biotechnology, Jeppiaar Engineering College, Old Mamallapuram Road, Rajiv Gandhi Salai, Semmenchery Village, Chennai-600 119, Tamil Nadu, India.
  2. Associate Professor, Department of Biotechnology, Jeppiaar Engineering College, Old Mamallapuram Road, Rajiv Gandhi Salai, Semmenchery Village, Chennai-600 119, Tamil Nadu, India.
  3. Department of Biomedical Enginerring, Sathyabama University, Rajiv Gandhi Road, Jeppiar Nagar Chennai 600 119, Tamil Nadu, India
  4. Department of Crop Science, Tshwane University of Technology, Pretoria Campus (West), Pretoria 0001, South Africa
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Abstract

This study aimed to elucidate of Leucas aspera, the plant has been widely used as traditionally an antipyretic and insecticide. Different solvent extracts of L. aspera using Chicken Chorioallantoic Membrane (CAM) assay. Methanol leaf extract showed the maximum angiosuppressive activity of 3±1 inhibition, concentration-dependently displayed a strong inhibition in the chick chorioallantoic membrane (CAM) angiogenesis. The results thus suggest that, the plant Leucas aspera should be considered as a useful source for designing drugs to cure antiangiogenesis.

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