Ankle-Brachial Index as a Predictor of Cardiovascular Risk in Atrial Fibrillation
|Carmelo Radellini2, Egle Corrado1, Giuseppe Coppola2, Giuseppina Novo1 and Salvatore Novo2*|
|1Chair of Cardiovascular Disease, Center for the Early Diagnosis of Preclinical and Multifocal Atherosclerosis, The Secondary Prevention, University of Palermo, Italy|
|2Division of Cardiology, Department of Internal Medicine and Cardiovascular Disease, Hospital “P. Giaccone” of Palermo, Italy|
|Corresponding Author :||Prof. Salvatore Novo
Division of Cardiology
Department of Internal Medicine and Cardiovascular Disease
Hospital “P. Giaccone”, Via Vespro
29 - 90127 Palermo, Italy
E-mail: [email protected]
|Received: February 13, 2012; Accepted: November 24, 2012; Published: November 27, 2012|
|Citation: Radellini C, Corrado E, Coppola G, Novo G, Novo S (2012) Ankle- Brachial Index as a Predictor of Cardiovascular Risk in Atrial Fibrillation. J Clin Exp Cardiolog 3:224. doi:10.4172/2155-9880.1000224|
|Copyright: © 2012 Radellini C, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
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Objectives: Atrial Fibrillation (AF), the most frequent sustained arrhythmia, is associated with a high rate of morbidity and mortality. The clinical course of AF is often complicated by cardiovascular and cerebrovascular adverse events that usually have a dual origin: cardio embolic and atherothrombotic. The aim of our study is to demonstrate the existence of a relationship between Systemic Atherosclerosis and AF. More specifically, we have analysed the prevalence of lower limb Peripheral Artery Disease (PAD) in a population of fibrillating patients, and we have assessed whether the coexistence of AF and PAD might result in increased cardiovascular risks.
Methods: The study has been conducted on 200 patients, consecutively engaged, divided into patients with and without AF. All patients were subjected to a cardiovascular risk profile evaluation, a measurement of Ankle-Brachial- Index (ABI), and an estimation of the prevalence of cerebrovascular and cardiovascular events.
Results: The obtained results showed that the prevalence of PAD is higher in patients with AF, and these patients have also shown a higher prevalence of cerebrovascular and cardiovascular events. In addition, stratifying cases and controls according to the presence of PAD, we showed that there’s a higher prevalence of cardiovascular and cerebrovascular adverse events in people with both conditions associated.
Conclusions: The results affirm that patients with a history of AF have a higher rate of cerebrovascular disease, and patients with PAD and AF have a higher rate of coronary disease, suggesting that measurements of ABI and diagnosis and search for AF should be encouraged.