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Ankle-Brachial Index as a Predictor of Cardiovascular Risk in Atrial Fibrillation | OMICS International | Abstract
ISSN: 2155-9880

Journal of Clinical & Experimental Cardiology
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Research Article

Ankle-Brachial Index as a Predictor of Cardiovascular Risk in Atrial Fibrillation

Carmelo Radellini2, Egle Corrado1, Giuseppe Coppola2, Giuseppina Novo1 and Salvatore Novo2*
1Chair of Cardiovascular Disease, Center for the Early Diagnosis of Preclinical and Multifocal Atherosclerosis, The Secondary Prevention, University of Palermo, Italy
2Division of Cardiology, Department of Internal Medicine and Cardiovascular Disease, Hospital “P. Giaccone” of Palermo, Italy
Corresponding Author : Prof. Salvatore Novo
Division of Cardiology
Department of Internal Medicine and Cardiovascular Disease
Hospital “P. Giaccone”, Via Vespro
29 - 90127 Palermo, Italy
Tel: 3356889090-0916554301
E-mail: [email protected]
Received: February 13, 2012; Accepted: November 24, 2012; Published: November 27, 2012
Citation: Radellini C, Corrado E, Coppola G, Novo G, Novo S (2012) Ankle- Brachial Index as a Predictor of Cardiovascular Risk in Atrial Fibrillation. J Clin Exp Cardiolog 3:224. doi:10.4172/2155-9880.1000224
Copyright: © 2012 Radellini C, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Objectives: Atrial Fibrillation (AF), the most frequent sustained arrhythmia, is associated with a high rate of morbidity and mortality. The clinical course of AF is often complicated by cardiovascular and cerebrovascular adverse events that usually have a dual origin: cardio embolic and atherothrombotic. The aim of our study is to demonstrate the existence of a relationship between Systemic Atherosclerosis and AF. More specifically, we have analysed the prevalence of lower limb Peripheral Artery Disease (PAD) in a population of fibrillating patients, and we have assessed whether the coexistence of AF and PAD might result in increased cardiovascular risks.
Methods: The study has been conducted on 200 patients, consecutively engaged, divided into patients with and without AF. All patients were subjected to a cardiovascular risk profile evaluation, a measurement of Ankle-Brachial- Index (ABI), and an estimation of the prevalence of cerebrovascular and cardiovascular events.
Results: The obtained results showed that the prevalence of PAD is higher in patients with AF, and these patients have also shown a higher prevalence of cerebrovascular and cardiovascular events. In addition, stratifying cases and controls according to the presence of PAD, we showed that there’s a higher prevalence of cardiovascular and cerebrovascular adverse events in people with both conditions associated.
Conclusions: The results affirm that patients with a history of AF have a higher rate of cerebrovascular disease, and patients with PAD and AF have a higher rate of coronary disease, suggesting that measurements of ABI and diagnosis and search for AF should be encouraged.

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