Anticholinergic Use and Misuse in Psychiatry: A Comprehensive and Critical ReviewWadih J Naja and Athar Halaby*
Faculty of Medicine, Lebanese University, Lebanon
- *Corresponding Author:
- Athar Halaby
Faculty of Medicine
Lebanese University, Lebanon
E-mail: [email protected]
Received Date: March 28, 2017; Accepted Date: April 29, 2017; Published Date: April 30, 2017
Citation: Naja WJ, Halaby A (2017) Anticholinergic Use and Misuse in Psychiatry: A Comprehensive and Critical Review. J Alcohol Drug Depend 5:263. doi: 10.4172/2329-6488.1000263
Copyright: © 2017 Naja WJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Anticholinergic medications such as Trihexyphenidyl; Biperidine are widely prescribed to prevent or to treat extrapyramidal side effects produced by neuroleptic drugs. Concomitant use of anticholinergic drugs is more common with the first generation antipsychotic medications. There is a considerable body of data suggesting that anticholinergic drugs have a potential of abuse. In this article, we review the psychiatric use, mechanism of action and the abuse of each anticholinergic drug.