Anti-diabetic Activities of the Fruit Aegle mamelos
|Repon kumer Saha*, Arfatoon Nesa, Kamrun Nahar and Mahfuja Akter|
|Department of Pharmacy, East West University, Dhaka, Bangladesh|
|*Corresponding Author :||Repon kumer Saha
Department of Pharmacy
East West University, Dhaka, Bangladesh
Tel: +880 2-8811381
E-mail: [email protected],edu/[email protected]
|Received January 27, 2016; Accepted February 16, 2016; Published February 18, 2015|
|Citation: Saha RK, Nesa A, Nahar K, Akter M (2016) Anti-diabetic Activities of the Fruit Aegle mamelos. J Mol Biomark Diagn 7:272. doi:10.4172/2155-9929.1000272|
|Copyright: © 2016 Saha RK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
Objective: The objective of this study is pharmacological activities investigation of Aegle marmelos fruit.
Methods: After getting the sample (fruit) as dried powder, some sample was used for lactin isolation by ammonium sulphate precipitation method and some were used for methanolic extraction. Vacuum liquid chromatography (VLC), Thin layer chromatography (TLC) were used to detect the presence of various types of compound in rind. Presence of carbohydrate and proteins were investigated by thin layer chromatography. In vitro anti-diabetic assay was carried out by glucose uptake in yeast cells. Disc diffusion assay was performed to show the antibacterial effect using gram positive and gram negative strains of bacteria.
Result: Two extracts were used. One was methanolic extract and another was lectin extract. VLC fraction of methanolic extract of the Aegle marmelos fruit contains flavonoids and other biologically active compounds. The extract showed antibacterial activities against several bacteria. The lectin extract also showed antibacterial and anti-diabetic activity.
Conclusion: Therefore, Aegle marmelos may be considered as a plant of various health benefits.