Journal of Molecular Biomarkers & Diagnosis

Anti-diabetic Activities of the Fruit Aegle mamelos

Abstract

Repon kumer Saha, Arfatoon Nesa, Kamrun Nahar and Mahfuja Akter

Objective: The objective of this study is pharmacological activities investigation of Aegle marmelos fruit.

Methods: After getting the sample (fruit) as dried powder, some sample was used for lactin isolation by ammonium sulphate precipitation method and some were used for methanolic extraction. Vacuum liquid chromatography (VLC), Thin layer chromatography (TLC) were used to detect the presence of various types of compound in rind. Presence of carbohydrate and proteins were investigated by thin layer chromatography. In vitro anti-diabetic assay was carried out by glucose uptake in yeast cells. Disc diffusion assay was performed to show the antibacterial effect using gram positive and gram negative strains of bacteria.

Result: Two extracts were used. One was methanolic extract and another was lectin extract. VLC fraction of methanolic extract of the Aegle marmelos fruit contains flavonoids and other biologically active compounds. The extract showed antibacterial activities against several bacteria. The lectin extract also showed antibacterial and anti-diabetic activity.

Conclusion: Therefore, Aegle marmelos may be considered as a plant of various health benefits.