Anti-Inflammatory Cytokines in Sepsis: Immunological Studies and In Silico Investigation
- *Corresponding Author:
- Andréia Patrícia Gomes
Departamento de Medicina e Enfermagem
Universidade Federal de Viçosa, Avenida P. H. Rolfs, s/n
Campus Universitário, CEP: 36571-000 - Viçosa (MG), Brasil
Tel: (31) 3899-3978
E-mail: [email protected]
Received date: June 10, 2016; Accepted date: July 28, 2016; Published date: August 12, 2016
Citation: Gomes AP, Alves DLS, Miguel PSB, Inoue VH, Correia Lopes TC et al. (2016) Anti-Inflammatory Cytokines in Sepsis: Immunological Studies and In Silico Investigation. J Pharma Care Health Sys 3:166. doi:10.4172/2376-0419.1000166
Copyright: © 2016 Gomes AP et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The pathophysiology, diagnosis, treatment and prognosis of sepsis remain major challenges for contemporary clinical practice. In this sense, efforts to broaden the knowledge about the mechanisms involved in systemic inflammation and to identify new methods for detecting sepsis in the early stages and the stratification of patients are extremely important. The purpose of this paper is to review the role of the anti-inflammatory cytokines in sepsis and present perspectives on the in silico investigation of the role of these mediators in this nosological entity, using the computational system AutoSimmune.