alexa Antimicrobial Activity of the Crude Extracts and Fractions of Three Baccharis Species
ISSN: 2161-0444

Medicinal Chemistry
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Antimicrobial Activity of the Crude Extracts and Fractions of Three Baccharis Species

Tatiana Zuccolotto1, Félix Lourenço AV1, Estevan Bruginski1, Bruna Alves1, Andressa Veiga2, Fabio Seigi Murakami2 and Francinete Ramos Campos1*

1Department of Pharmacy, Biosciences Laboratory with Emphasis on Mass Spectrometry, Federal University of Paraná, Curitiba, Brazil

2Department of Pharmacy, Quality Control Laboratory Microbiology, Federal University of Paraná, Curitiba, Brazil

*Corresponding Author:
Ramos Campos F
Department of Pharmacy, Federal University of Parana
Av. Lothario Meissner, Botanical Gardens, Curitiba, Brazil
Tel: +554133604162
E-mail: [email protected]

Received date: August 24, 2016; Accepted date: August 27, 2016; Published date: August 31, 2016

Citation: Zuccolotto T, Félix Lourenço AV, Bruginski E, Alves B, Veiga A, et al. (2016) Antimicrobial Activity of the Crude Extracts and Fractions of Three Baccharis Species. Med Chem (Los Angeles) 6:557-560. doi:10.4172/2161-0444.1000399

Copyright: © 2016 Zuccolotto T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



The antimicrobial activities of crude extracts and fractions from three Baccharis L. species were tested against Staphylococcus aureus (ATCC 6538), Escherichia coli (ATCC 8738), Pseudomonas aeruginosa (ATCC 9027), and Candida albicans (ATCC 10231) using the microdilution plate method. The results showed that the crude extract from female B. burchellii Baker had moderate activity against S. aureus (minimum inhibitory concentration [MIC], 0.9 mg.mL-1). Among the fractions obtained from this extract, the dichloromethane fraction showed the highest activity against S. aureus (MIC, 0.4 mg.mL-1). The ethyl acetate fractions from female B. burchellii (MIC, 0.6 mg.mL-1 and 1.2 mg.mL-1, respectively) and B. aracatubaensis Malag (MIC, 1.1 mg.mL-1 for both) were moderately effective against S. aureus and P. aeruginosa. The extracts from B. organensis Baker showed no significant activity against any organism tested. None of the extracts from Baccharis species showed any activity against C. albicans. In addition, the chemical investigation of the dichloromethane and ethyl acetate fractions from female B. burchellii was carried out, resulting in the identification of trans-ferulic acid, ethyl caffeoate, naringenin, and 7-hydroxy-benzaldehyde compounds. These phenolic compounds were found in other species of Baccharis and have been shown to possess antimicrobial activity. The results obtained in this work with respect to B. burchellii indicate that this species is a promising source of compounds with antimicrobial activities.


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version