Anti-myelin Oligodendrocyte Glycoprotein Autoantibodies in Optic Neuritis and Venous Sinus Thrombosis in a GirlVictor Soto-Insuga*, Thais Armangue Salvador, Laura Cabrejas Martinez, Rebeca Losada del Pozo, Maria Rodrigo Moreno, Cristina Ordonez Gonzalez and Jesus Rodriguez Catalan
Department of Pediatrics, Jimenez Diaz Foundation, Madrid, Spain
- *Corresponding Author:
- Victor Soto-Insuga
Department of Pediatrics
Jimenez Diaz Foundation, Madrid, Spain
E-mail: [email protected]
Received date: January 19, 2016 Accepted date: March 8, 2016 Published date: March 13, 2016
Citation: Insuga VS, Salvador TA, Martinez LC, del Pozo RL, Moreno MR, et al. (2016) Anti-myelin Oligodendrocyte Glycoprotein Autoantibodies in Optic Neuritis and Venous Sinus Thrombosis in a Girl. J Pediatr Neurol Med 1:109. doi:10.4172/2472-100X.1000109
Copyright: © 2016 Soto-Insuga V, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The anti-myelin oligodendrocyte glycoprotein autoantibody (anti-MOG) is recognized as a new diagnostic and prognostic markers in paediatric acquired demyelinating diseases of the central nervous system. We report a 6 years gril who developed a venous sinus thrombosis and signs of intracranial hypertension after acute otitis media. One month after this infection the patient had an episode of unilateral optic neuritis associated with anti-MOG in serum. Our patient received intravenous steroid treatment and showed a highly favourable response. This is the first case report of demyelinating disease with anti-MOG antibodies associated with thrombophilia.