alexa Anti-myelin Oligodendrocyte Glycoprotein Autoantibodies in Optic Neuritis and Venous Sinus Thrombosis in a Girl | OMICS International| Abstract

ISSN: 2472-100X

Journal of Pediatric Neurology and Medicine

  • Case Report   
  • J Pediatr Neurol Med 2016, Vol 1(2): 2
  • DOI: 10.4172/2472-100x.1000109

Anti-myelin Oligodendrocyte Glycoprotein Autoantibodies in Optic Neuritis and Venous Sinus Thrombosis in a Girl

Victor Soto-Insuga*, Thais Armangue Salvador, Laura Cabrejas Martinez, Rebeca Losada Del Pozo, Maria Rodrigo Moreno, Cristina Ordonez Gonzalez and Jesus Rodriguez Catalan
Department of Pediatrics, Jimenez Diaz Foundation, Madrid, Spain
*Corresponding Author : Victor Soto-Insuga, Department of Pediatrics, Jimenez Diaz Foundation, Madrid, Spain, Tel: 034660565897, Email: [email protected]

Received Date: Jan 19, 2016 / Accepted Date: Mar 08, 2016 / Published Date: Mar 13, 2016

Abstract

The anti-myelin oligodendrocyte glycoprotein autoantibody (anti-MOG) is recognized as a new diagnostic and prognostic markers in paediatric acquired demyelinating diseases of the central nervous system. We report a 6 years gril who developed a venous sinus thrombosis and signs of intracranial hypertension after acute otitis media. One month after this infection the patient had an episode of unilateral optic neuritis associated with anti-MOG in serum. Our patient received intravenous steroid treatment and showed a highly favourable response. This is the first case report of demyelinating disease with anti-MOG antibodies associated with thrombophilia.

Keywords: Anti-myelin oligodendrocyte glycoprotein autoantibody (Anti-Mog); Aquoporin-4 antibodies (Aqp-4); Optic neuritis; Venous sinus thrombosis

Citation: Insuga VS, Salvador TA, Martinez LC, del Pozo RL, Moreno MR, et al. (2016) Anti-myelin Oligodendrocyte Glycoprotein Autoantibodies in Optic Neuritis and Venous Sinus Thrombosis in a Girl. J Pediatr Neurol Med 1: 109. Doi: 10.4172/2472-100x.1000109

Copyright: ©2016 Insuga VS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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