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ISSN: 2161-1009

Biochemistry & Analytical Biochemistry
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Review Article

Antioxidant Potential of Phycobiliproteins: Role in Anti-Aging Research

Ravi Raghav Sonani*, Rajesh Prasad Rastogi and Datta Madamwar*

BRD School of Biosciences, Vadtal Road, Satellite Campus, Post Box No. 39, Sardar Patel University, Gujarat, India

*Corresponding Author:
Sonani RR
BRD School of Biosciences
Vadtal Road, Satellite Campus
Post Box No. 39, Sardar Patel University
Vallabh Vidyanagar 388 120
Anand, Gujarat, India
Tel: +91 02692 229380
Fax: +91 02692 236475
E-mail: [email protected]

Madamwar D
BRD School of Biosciences
Vadtal Road, Satellite Campus
Post Box No. 39, Sardar Patel University
Vallabh Vidyanagar 388 120
Anand, Gujarat, India
Tel: +91 02692 229380
Fax: +91 02692 236475
E-mail: [email protected]

Received Date: January 30, 2015; Accepted Date: April 10, 2015; Published Date: April 14, 2015

Citation: Sonani RR, Rastogi RP, Madamwar D (2015) Antioxidant Potential of Phycobiliproteins: Role in Anti-Aging Research. Biochem Anal Biochem 4:172. doi: 10.4172/2161-1009-1000172

Copyright: © 2015 Sonani RR, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Aging research has made significant progress over recent years, particularly after the formulation of ‘Oxidative stress theory of aging’. According to this theory, aging and its associated abnormalities may be prevented, at least to some extent, by application of certain antioxidants. Cyanobacterial phycobiliproteins (PBPs), the major light harvesting pigment proteins are widely characterized for their in vivo and in vitro antioxidant activity. Since, reactive oxygen species (ROS) are considered as important factors to cause aging, PBPs can be used as an effective free radical scavengers and be a potent candidate to develop the anti-aging drug. The use of PBPs in preventing the oxidative stress mediated abnormalities or aging is rationally debated. The present review enlightens the recent advances in the field of antioxidant function of PBPs and major challenges in the application of these pigment proteins in anti-aging research. Also included is the possible mechanism behind the anti-aging capacity of these ecologically as well as economically important biomolecules.

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