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ISSN: 2329-9029

Journal of Plant Biochemistry & Physiology
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Research Article

Antitoxic, Antifungal and Phytochemical Analysis of Medicinal Compounds of Guiera senegalensis Leaves in Sudan

Nabaa Kamal Al Shafei1*, Abdulkadir Elzein Elshafie2 and Abdelfattah Nour3
1Department of Biochemistry, Faculty of Veterinary Medicine, University of Bahri, Sudan
2Department of Biology, College of Science, Sultan Qaboos University, Oman
3Department of Basic Medical Sciences, College of Veterinary Medicine, Purdue University, USA
*Corresponding Author : Nabaa Kamal Al Shafei
Department of Biochemistry, College of Veterinary Medicine
University of Bahri, Khartoum, Sudan
Tel: +249122410042
E-mail: [email protected]
Received: March 11, 2016 Accepted: March 30, 2016 Published: April 07, 2016
Citation: Shafei NKA, Elshafie AE, Nour A (2016) Antitoxic, Antifungal and Phytochemical Analysis of Medicinal Compounds of Guiera senegalensis Leaves in Sudan. J Plant Biochem Physiol 4:166. doi:10.4172/2329-9029.1000166
Copyright: © 2016 Shafei NKA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Guiera senegalensis (Gs) is a well-known traditional medicinal plant in Africa, whose leaves extract and roots powder are used for treatment of diseases and wounds in Western Kordufan, Sudan. The aim of this study was to investigate the phytochemical analysis, toxicity, and the antifungal activity of Gs leaves extract. Extract of the leaves of Gs was tested for its antimicrobial activity against Stemphylium solani, Aspergillus flavus, Trichoderma viride, Penicillium Spp., Fusarium verticillatum, Cladosporium cladosporioides, and Fusarium solani. This present study showed that Gs leaves extract has no inhibition activity against all of the tested fungal strains. On the other hand, the toxicity test, which was conducted by using brine shrimp, suggests that Gs leaves extract is apparently not toxic. The phytochemical screening revealed that Gs leave extract contains alkaloids, flavonoids, terpenoids, tannin, carbohydrates, proteins, steroids, and saponins. The results of this preliminary investigation suggests that the medicinal plant extract may be safe to use as a drink for treatment of various diseases as has been practiced for years in the villages of Western Sudan. More research is needed to investigate if there is any side effect when the extract is taken orally. Further, the medicinal properties of the phytochemical compounds of Gs need to be further investigated.

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