alexa Anti-Tumor, Antioxidant and Antimicrobial and the Phenolic Constituents of Clove Flower Buds (Syzygium aromaticum) | OMICS International | Abstract
ISSN: 1948-5948

Journal of Microbial & Biochemical Technology
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Research Article

Anti-Tumor, Antioxidant and Antimicrobial and the Phenolic Constituents of Clove Flower Buds (Syzygium aromaticum)

Abd El Azim M H M1*, Amani M D El-Mesallamy1, El-Gerby M1, and Awad A2

1Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt

2Medicinal and Aromatic Plants Department, Desert Research Center, Cairo, Egypt

3Department of Chemistry, Faculty of Science, Jazan University, Jizan 2097, Saudi Arabia

*Corresponding Author:
Abd El Azim MHM
Department of Chemistry
Faculty of Science, Zagazig University
Zagazig, Egypt
Tel: 00201147073479
E-mail: [email protected]

Received date: September 22, 2014; Accepted date: October 09, 2014; Published date: October 16, 2014

Citation: Abd El Azim MHM, El-Mesallamy AMD, El-Gerby M, Awad A (2014) Anti-Tumor, Antioxidant and Antimicrobial and the Phenolic Constituents of Clove Flower Buds (Syzygium aromaticum). J Microb Biochem Technol S8:007. doi: 10.4172/1948-5948.S8-007

Copyright: © 2014 Abd El Azim MHM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Abstract

Eleven phenolic compounds were identified from the methanolic extract of Cloves flowers buds (Syzygium aromaticum L.) by chromatographic methods. Efficiency of the methanolic extract of licorice roots as anticancer agent for breast, colon and liver was tested. The results showed that the IC50 were (31 μg/mL for anti-colon cancer, 29.7 μg/ml for anti-breast cancer and 18.7 μg /ml for anti-hepatic cancer). This extract showed strong antioxidant activity against 2, 2-diphenyl-1-picrylhydrazyl (DPPH.) as compared with vitamin C. Antimicrobial activity of the methanol extract of licorice roots was studied against three bacterial and four fungal strains at concentration 0.1 ml and 0.3 ml (10 mg/1 ml)). The extract showed strong inhibitory effect for most species at concentration 0.3 ml (10 mg/ ml).

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