Application of Bap-65: A New Score for Risk Stratification in Acute Exacerbation of Chronic Obstructive Pulmonary DiseaseRabih Tabet*, Charbel Ardo, Paul Makhlouf and Jeff Hosry
Department of Cardiovascular Medicine, Faculty of Medical Sciences, The Lebanese University, Hadath, Beirut, Lebanon
- *Corresponding Author:
- Rabih Tabet, MD
Department of Cardiovascular Medicine
Faculty of Medical Sciences
The Lebanese University, Hadath, Beirut, Lebanon
E-mail: [email protected]
Received March 15, 2016; Accepted March 18, 2016; Published March 21, 2016
Citation: Tabet R, Ardo C, Makhlouf P, Hosry V (2016) Application of Bap-65: A New Score for Risk Stratification in Acute Exacerbation of Chronic Obstructive Pulmonary Disease. J Clin Respir Dis Care 2:110. doi: 10.4172/2472-1247.1000110
Copyright: © 2016 Tabet R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background and objectives: COPD is gaining importance in the field of public health because it is expected to become the third leading cause of death worldwide by 2020. Until today, there is no validated score for risk stratification of patients presenting with an exacerbation of COPD to the emergency department. The BAP-65 is a new score, published in 2011 in the «CHEST» journal, which was used to predict the need for mechanical ventilation and predict the risk of mortality in acute exacerbation of COPD. Thus, we decided to conduct this study and apply the BAP-65 score in Lebanon, in order to test its accuracy in correlating the clinical and biological status of the patient presenting with acute exacerbation of COPD with mortality risk and the possible use of MV. Methods: We analysed 980 admissions to two Lebanese hospitals (2005 through 2013) with a discharge diagnosis of acute exacerbation of COPD. The primary endpoints were hospital mortality and need for MV. We used the SPSS program - Version 17 in our analysis. Results:170 patients (17.3%) required mechanical ventilation and 59 patients (6%) passed away during hospitalization. Statistics showed that both end points increased with increasing BAP-65. 1.3% of patients with a score of 0 or 1 needed intubation, while 74% of patients with a score of 3 or 4 were intubated (P-value < 0.001). Moreover, <1% of patients with a score of 0 or 1 passed away, while 51% of patients with a score of 3 or 4 died (P-value < 0.001). Conclusions: The BAP-65 scoring system seems to be a useful and simple tool to classify the patients presenting with AECOPD, and it correlates with both need for mechanical ventilation and mortality. Most importantly, it showed consistent results when applied in different populations.