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Application of Box Behnken Experimental Design to Analysis Reaction Conversion of n-Butyl Acetate to n-Butanol | OMICS International | Abstract
ISSN: 2090-4568

Journal of Advanced Chemical Engineering
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Research Article

Application of Box Behnken Experimental Design to Analysis Reaction Conversion of n-Butyl Acetate to n-Butanol

Firuz Fakheri*, Ali Sharif Alam, Shokrollah Mohseni and Ramin Ramezani Kalhor

Shifa Pharmed Industrial Group, Karaj, Iran

*Corresponding Author:
Firuz Fakheri
Shifa Pharmed Industrial Group, Karaj, Iran
Tel: 9367341446
E-mail: [email protected]

Received Date: May 08, 2014; Accepted Date: August 04, 2014; Published Date: August 11, 2014

Citation: Fakheri F, Alam AS, Mohseni S, Kalhor RR (2014) Application of BoxBehnken Experimental Design to Analysis Reaction Conversion of n-Butyl Acetate to n-Butanol. J Adv Chem Eng 4:110. doi:10.4172/2090-4568.1000110

Copyright: © 2014 Fakheri F, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


In this paper Box Behnken was used to study the effect and optimization of reaction temperature, percentage of n -butyl acetate, value of sodium hydroxide on the percentage of reaction conversion of n -butyl acetate to n -butanol. The mathematical relationship of percentage of reaction conversion on three significant independent variables can be approximated by a nonlinear polynomial model. The analysis of experimental design showed that the percentage of reaction conversion was increased by increasing the temperature and value of n -butyl acetate. Results show that the excess value of sodium hydroxide has less effect on the percentage reaction conversion than the other variables and the percentage reaction conversion was found to be strongly affected by the temperature of reaction.

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