alexa Are Periventricular Lesions Specific for Multiple Sclerosis? | OMICS International | Abstract
ISSN: 2155-9562

Journal of Neurology & Neurophysiology
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Are Periventricular Lesions Specific for Multiple Sclerosis?

Gianna Casini, Mary Yurashevich, Rohini Vanga, Subasini Dash, Suhayl Dhib-Jalbut, Brian Gerhardstein, Matilde Inglese, Win Toe and Konstantin E Balashov*

Department of Neurology, Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA

Corresponding Author:
Konstantin E. Balashov
125 Paterson Street
6th Floor New Brunswick, NJ, 08901, USA
Tel: (732)235-7727
Fax: (732)906-5705
E-mail: [email protected]

Received date: March 15, 2013; Accepted date: April 27, 2013; Published date: May 03, 2013

Citation: Casini G, Yurashevich M, Vanga R, Dash S, Dhib-Jalbut S, et al. (2013) Are Periventricular Lesions Specific for Multiple Sclerosis? J Neurol Neurophysiol 4:150. doi:10.4172/2155-9562.1000150

Copyright: © 2013 Casini G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: The presence of periventricular lesions (PVL) on MRI scans is part of the revised McDonald
multiple sclerosis (MS) diagnostic criteria. However, PVL can be found in other neurological diseases including stroke
and migraine. Migraine is highly prevalent in patients with MS.
Objective: To determine if PVL are specific for patients with MS compared to stroke and migraine.
Methods: We studied patients diagnosed with clinically isolated syndrome (CIS), relapsing-remitting MS (RRMS),
migraine, and ischemic stroke. The number, location and the volume of PVL were identified on brain MRI scans and
analyzed.
Results: The number and volume of PVL adjacent to the body and the posterior horn of the lateral ventricles
were significantly increased on fluid-attenuated inversion recovery MRI in RRMS compared to migraine. There were
no significant differences in the total number and volume of PVL in ischemic stroke patients compared to the agematched
RRMS patients nor in the number and volume of PVL adjacent to the anterior and temporal horns of the
lateral ventricles on FLAIR images in migraine compared to CIS or RRMS.
Conclusion: In contrast to PVL adjacent to the body and the posterior horn of the lateral ventricles, PVL adjacent
to the anterior and temporal horns of the lateral ventricles may not be specific for CIS/RRMS when compared to
migraine, the disease highly prevalent among patients with MS. PVL are not specific for MS when compared to
ischemic stroke.

Keywords

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7