alexa Aromatic and Steroid Compounds from Smilax Bracteata C.
ISSN: 2329-6836

Natural Products Chemistry & Research
Open Access

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Research Article

Aromatic and Steroid Compounds from Smilax Bracteata C. Presl. (Smilacaceae), a Bornean Medicinal Herb

Julius Kulip*, Takashi Kamada and Charles SV
Institute for Tropical Biology and Conservation, Universiti Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, Malaysia
Corresponding Author : Julius Kulip
Institute for Tropical Biology and Conservation
Universiti Malaysia Sabah, Jalan UMS
88400 Kota Kinabalu, Sabah, Malaysia
Tel: 60 88-320 000
E-mail: [email protected]
Received July 13, 2015; Accepted August 01, 2015; Published August 03, 2015
Citation: Kulip J, Kamada T, Charles SV (2015) Aromatic and Steroid Compounds from Smilax Bracteata C. Presl. (Smilacaceae), a Bornean Medicinal Herb. Nat Prod Chem Res 3:184. doi:10.4172/2329-6836.1000184
Copyright: © 2015 Kulip J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

The medicinal herbs, Smilax bracteata C. Presl. (Smilacaceae) or commonly known as Tongkung in North Borneo Island was used traditionally for treatment of ailments in various Dusun villages in Sabah, Malaysia. One aromatic compound seselin (1) and two steroids β-sitosterol (2) as well as stigmasti-4-ene-3-one (3) were isolated and identified as major secondary metabolites from this plant. Their chemical structures were elucidated using 1H, 13C and 2D NMR. These chemical compounds have shown to possess variety of biological activities such as anticancer, anti-fungal and anti-inflammatory. Therefore, the ailments of local native Dusun people in Sabah, Malaysia were treated due to the presence of these compounds in S. bracteata.

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