alexa Arsenic Exposure: Mechanisms of Action and Related Health Effects
ISSN: 2161-0525

Journal of Environmental & Analytical Toxicology
Open Access

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Research Article

Arsenic Exposure: Mechanisms of Action and Related Health Effects

Bilal Ahmad Tantry1,2*, Divya Shrivastava2, Ibrahim Taher1 and Mudasar Nabi Tantry3
1Department of Microbiology, College of Medicine, Aljouf University, Saudi Arabia
2School of Life Sciences, Jaipur National University, Jaipur, India
3Department of Clinical Biochemistry, Kashmir University, India
Corresponding Author : Bilal Ahmad Tantry
Department of Microbiology
College of Medicine, Aljouf University
Saudi Arabia
Tel: 966506281724
E-mail: [email protected]
Received: August 17, 2015; Accepted: October 25, 2015; Published: October 28, 2015
Citation: Tantry BA, Shrivastava D, Taher I, Tantry MN (2015) Arsenic Exposure: Mechanisms of Action and Related Health Effects. J Environ Anal Toxicol 5:327. doi:10.4172/2161-0525.1000327
Copyright: © 2015 Tantry BA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Arsenic represents a natural drinking water contaminant that can deteriorate health due to its extreme toxic nature. Infant mortality, neuropathies, liver disease, cancer, eye diseases, cardiovascular disease and different skin alterations can stem from chronic arsenic exposure. The predominant species of arsenic comprise of arsenite and arsenate. Arsenite is more toxic in nature as compared to arsenate. Arsenic pollution is mainly caused by natural process such as weathering of rocks and minerals followed by leaching and industrial activities that lead to contamination of soil and groundwater. The WHO guideline permits the maximum limit of arsenic as 10 μg/L in drinking water. This review provides a comprehensive overview on arsenic mode of action, its sources and health related effects. The effect of toxicity, biomarkers of arsenic toxicity and the mechanism of arsenic dangers on humans are also discussed.

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