Ascorbic Acid in Cancer: A Renewed Hope?
- *Corresponding Author:
- Sunil Rangarajan
MBBS, 2nd Avenue South
LHRB 452, 1720 Birmingham
Alabama – 35294, University of Alabama at Birmingham
E-mail: [email protected]
Received date: May 06, 2014; Accepted date: August 28, 2014; Published date: September 03, 2014
Citation: Rangarajan S, Sunil B, Curtis LM (2014) Ascorbic Acid in Cancer: A Renewed Hope? J Cancer Sci Ther 6:333-336. doi:10.4172/1948-5956.1000291
Copyright: © 2014 Rangarajan S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Ascorbic acid (AA), long known to treat scurvy, has had debatable use as an anti-neoplastic drug in the past. However recent in vitro and in vivo studies have revealed previously unexplored mechanisms through which AA selectively damages cancer cells without causing damage to normal cells. In view of newly emerging evidence, many clinical trials have been designed to study these effects in patients with different types of cancers. Promising results from these initial trials are giving renewed hope to the use of AA as an adjuvant to the conventional chemotherapeutic drugs to treat cancer, to alleviate toxicity from the treatment and to reduce patient morbidity.