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ISSN: 2329-9495

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Research Article

Assesment of Autonomic Function in Slow Coronary Flow using Heart Rate Variability and Heart Rate Turbulence

Savas Sarıkaya1*, Fatih Altunkas2, Kayıhan Karaman2, Safak Sahin3, Lutfu Akyol4, Elif Borekci4 and Yunus Keser Yılmaz5

1Department of Cardiology, Bozok University, Yozgat, Turkey

2Department of Cardiology, Gaziosmanpasa University, Tokat, Turkey

3Department of Internal Medicine, Gaziosmanpasa University, Tokat, Turkey

4Department of Internal Medicine, Bozok University, Yozgat, Turkey

5Department of Cardiovascular Surgery, Bozok University, Yozgat, Turkey

*Corresponding Author:
Savas Sarikaya
Department of Cardiology, Bozok University, Yozgat, Turkey
Tel: +903542126070
Fax: +903542126070
E-mail: [email protected]

Received Date: July 24, 2013; Accepted Date: October 29, 2013; Published Date: October 31, 2013

Citation: Sarikaya S, Altunkas F, Karaman K, Sahin S, Akyol L, et al. (2014) Assesment of Autonomic Function in Slow Coronary Flow using Heart Rate Variability and Heart Rate Turbulence. Angiol 2:117. doi: 10.4172/2329-9495.1000117

Copyright: © 2014 Sarikaya S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Background: Slow Coronary Flow Syndrome (SCFS) is an angiographic observation characterized by angiographically normal or near-normal coronary arteries with the delayed progression of contrast dye injected into the coronary tree. Previous studies suggested that these patients had autonomic dysfunction. Life threatening arrhythmias and sudden cardiac death have also been reported in these patients.

Aim: Our aim was to assess autonomic function in slow coronary patients using heart rate variability and heart rate turbulence.

Method: We selected 40 slow coronary patients and 30 healthy individuals with normal coronary. 24 hours ambulatory holter ECG recordings were obtained from all patients. Turbulence onset (TO), Turbulence slope (TS), Time domain HRV (SDNN, Mean RR, RMSSD, Pnn50 and triangular index (TI) were analysed and compared between two groups.

Results: There were no difference in Mean RR (ms), RMSSD (ms) and Total Snn50 between groups. But SDNN (ms) and Triangular index (TI) were different between groups.( 128.52 ± 9.32 vs 174.25 ± 73 p<0.001 and 31.74 ± 4.67 vs 42.48 ± 5.86 p<0.001 respectively). TO and TS were different between groups (1.06 ± 2.4 vs -0.16 ± 0.34 p: 0.009 and 9.47 ± 6.03 vs 14.41 ± 8.66 p: 0.021). There was a negative correlation between SDNN and mean TFC (r: -0.834 p<0.001) and positive correlation between TO and mean TFC (r:0.350 p:0.003).

Conclusion: We showed that some of HRV parameters and HRT was impaired in favor of slow coronary patients. Impaired autonomic activity may lead to the tendency to arrhythmias and may cause sudden cardiac death in slow coronary patients.


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