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ISSN: 2167-1044

Journal of Depression and Anxiety
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Research Article

Assessing Patient and Caregiver Experiences with Symptoms and Behaviors Associated with Schizophrenia

Dana B DiBenedetti1*, Michelle T Brown1 and Natalya Danchenko2

1RTI Health Solutions, Research Triangle Park, North Carolina, USA

2Lundbeck SAS, Cedex, France

*Corresponding Author:
Dana Britt DiBenedetti
PhD, Head, Patient-Reported Outcomes
RTI Health Solutions, 200 Park Offices Drive
Research Triangle Park, NC 27709 USA
Tel: +19193163764
Fax: +19193411960
E-mail: [email protected]

Received date: May 04, 2016; Accepted date: July 14, 2016; Published date: July 17, 2016

Citation: DiBenedetti DB, Brown MT, Danchenko N (2016) Assessing Patient and Caregiver Experiences with Symptoms and Behaviors Associated with Schizophrenia. J Depress Anxiety 5:240. doi:10.4200/2167-1044.1000240

Copyright: © 2016 DiBenedetti DB, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Objective: Obtaining patient and caregiver perspectives may be critical for informing disease management, particularly with conditions like schizophrenia. The primary objective of the current study was to obtain and assess patient and caregiver perspectives on associated symptoms and behaviors of schizophrenia and their impact or burden on patients and their caregivers through patient interviews and caregiver focus groups.

Research design and methods: Seven in-depth individual interviews were conducted with individuals with schizophrenia, and four focus groups were conducted with caregivers of adults with schizophrenia (n = 21) in two different locations in the United States. Following a discussion guide, interviewers asked open-ended questions to ascertain specific definitions and experiences related to five associated symptoms and behaviors (anxiety, irritability, agitation, impulsivity, and aggression), the impact of these symptoms, and how they were associated with schizophrenia. Additionally, patients completed the 8-item Birchwood Insight Scale developed to assess insight in patients with schizophrenia.

Results: The impacts of anxiety were the most widespread and persistent for the patients, primarily relating to social and family interactions and relationships. For both patients and caregivers, patients’ anxiety comprised a mental and a physical component and contributed to escalation of other emotions and behaviors. Other significant or debilitating impacts, such as emotional functioning, legal issues, and financial distress, were attributed to aggression and impulsivity for both the patients and the caregivers.

Conclusion: This study provides evidence of the impact of anxiety in the lives of patients with schizophrenia and their caregivers, and the potential relationship of and escalation from anxiety to aggression. Additionally, the study reinforces the importance of ensuring that treatment is taking into account the highly prevalent anxiety symptoms and behavioral disturbances in patients with schizophrenia as well as the implications of these symptoms and disturbances on the caregivers.

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