alexa Assessment of the Early Infant Diagnosis of HIV Infecti
ISSN 2155-6113

Journal of AIDS & Clinical Research
Open Access

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Research Article

Assessment of the Early Infant Diagnosis of HIV Infection in Togo in 2014

Azoumah KD1*, Agbeko F2, Segbedji Kar1, Djadou KE3, Takassi OE3, Fiawoo M3, Tchagbele OB3, Geraldo A1, Agbèrè AD2 and Atakouma DY3

1Department of Paediatrics, CHU-Kara, University of Kara, Kara, Togo

2Department of Paediatrics, CHR Lomé Commune, University of Lomé, Lomé, Togo

3Department of Paediatrics, CHU-Sylvanus Olympio, University of Lomé, Lomé, Togo

Corresponding Author:
Azoumah KD
Head of department
Universite de Kara/ CHU-Kara (Kara Teaching Hospital)
Paediatrics, Boulevard des Evala, Kara, Togo
Tel: 0022890019866
E-mail: [email protected]

Received date: May 02, 2017; Accepted date: May 18, 2017; Published date: May 25, 2017

Citation: Azoumah KD, Agbeko F, Kar S, Djadou KE, Takassi OE, et al. (2017) Assessment of the Early Infant Diagnosis of HIV Infection in Togo in 2014. J AIDS Clin Res 8:695. doi:10.4172/2155-6113.1000695

Copyright: © 2017 Azoumah KD, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Introduction: Early infant diagnosis (EID) of Human immunodeficiency virus (HIV) infection by Polymerase Chain Reaction (PCR) on Dry Blood Spot (DBS) has started in Togo since 2009 with difficulties about geographic accessibility and durability of the test. The aim of this study is to analyze the timeframes of implementation and the results of the PCR in Togo. Methodology: This was a cross-sectional study from 22 July to 15 August 2014 on PCR registers and application forms in the two reference laboratories in Togo (Lomé and Kara) and on clinical records of exposed children in 26 sites of Prevention of mother-to-child transmission (PMTCT). The analysis focused on the sampling, performance and test results. Results: The number of collected samples increased from 450 in 2011 to 920 in 2013, representing only 13% of the expected PCRs. However, 97% of these samples were sent to laboratories. The average age at PCR samples varied from 3.3 to 8.5 months. The main gateway was PMTCT (99.5%); the majority of children were breastfed (80.8%). The proportion of results returned to parents ranged from 12% to 52% between 2011 and 2013. The average duration between the dates of the sample’s withdrawal and the return of the result to the mother, calculated on clinical record, was 68 days (n=62) but could reach 105.5 days according to the health service providers. The rate of vertical transmission of HIV was 4.5%. Conclusion: The timeframes for the implementation of PCRs are long in Togo. Scaling up and creating an emergency fund will improve the early diagnosis of the child.

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