alexa Association of Microalbuminuria with Ischemic Heart Disease, Dyslipidemia andObesity among Diabetic Patients: Experience from 5 Year Follow up Study of1415 Patients
ISSN: 2167-7662

Bioenergetics: Open Access
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Research Article

Association of Microalbuminuria with Ischemic Heart Disease, Dyslipidemia andObesity among Diabetic Patients: Experience from 5 Year Follow up Study of1415 Patients

Kamran MA Aziz*
Diabetology Clinic, Aseer Diabetes Center of Aseer Central Hospital, Ministry of Health, Saudi Arabia
Corresponding Author : Kamran MA Aziz
Diabetology Clinic, Aseer Diabetes Center of Aseer Central Hospital
Ministry of Health, P.O.Box 34, Abha, Saudi Arabia
Tel: 96672251155
Fax: 96672265301
E-mail: [email protected]
Received April 25, 2014; Accepted June 20, 2014; Published June 23, 2014
Citation: Aziz KMA (2014) Association of Microalbuminuria with Ischemic Heart Disease, Dyslipidemia and Obesity among Diabetic Patients: Experience from 5 Year Follow up Study of 1415 Patients. Bioenergetics 3:118. doi:10.4172/2167-7662.1000118
Copyright: © 2014 Aziz KMA. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

This paper presents a microalbuminuria, a novel marker incipient nephropathy, and its simultaneous association at cross sectional level with ischemic heart disease, dyslipidemia and obesity among diabetic patients which has not been studied together in the past. Variables BMI, HbA1c, creatinine, total cholesterol, triglycerides, LDL-C, HDL-C, microalbuminuria, systolic and diastolic blood pressure were measured and compared for the two groups with and without IHD, nephropathy, dyslipidemia and obesity. Statistically it was observed that microalbuminuria, nephropathy, hypertension, and dyslipidemia were significantly associated with the development of ischemic heart disease (p-value < 0.0001 for all). Furthermore, Hypertension was significantly associated with nephropathy as obesity was associated with development of hypertension (p-value < 0.0001 for both variables). Additionally, it was demonstrated that both BMI and HDL-C were inversely and significantly correlated (p-value < 0.05). Both systolic and diastolic blood pressure significantly correlated with the development of microalbuminuria in this diabetic population (p-value < 0.0001 for both). Current study recommends screening diabetic patients early for microalbuminuria at primary care level, to target high BMI and HbA1c, early diagnosis and treatment of hypertension and dyslipidemia to prevent further diabetic complications and economic burden.

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