Asthma in HIV-Infected Population: A Review of Respiratory Symptoms, Pulmonary Function Abnormalities and Pathophysiology
- Corresponding Author:
- Matthew Gingo
3459 Fifth Ave. NW628 MUH
Pittsburgh, PA 15213, USA
E-mail: [email protected]
Received Date: May 27, 2014; Accepted Date: July 09, 2014; Published Date: July 16, 2014
Citation: Puri A, Gingo M, Morris A (2014) Asthma in HIV-Infected Population: A Review of Respiratory Symptoms, Pulmonary Function Abnormalities and Pathophysiology. Epidemiol 4:164. doi:10.4172/2161-1165.1000164
Copyright: © 2014 Gingo M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Asthma is prevalent around the world, requiring frequent hospital admissions and resulting in significant morbidity. National surveillance for asthma in the United States estimated the prevalence of asthma from 2006-2008 to be approximately 7.3% in adults, with the prevalence being higher in females (8.9%) than males (5.5%). The pathophysiology of asthma is characterized by inflammation and hyper-responsiveness of lung bronchioles. There is emerging evidence indicating an association between asthma and human immunodeficiency virus (HIV) infection, but much remains to be learned. The article will review the prevalence of respiratory symptoms, pulmonary function abnormalities and asthma in the HIV-infected population and summarize recent research focusing on potential mechanisms linking the two disease processes. In addition, we review important asthma treatment considerations in HIV-infected individuals.