alexa Asthma in HIV-Infected Population: A Review of Respirat
ISSN: 2161-1165

Epidemiology: Open Access
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Review Article

Asthma in HIV-Infected Population: A Review of Respiratory Symptoms, Pulmonary Function Abnormalities and Pathophysiology

Aditi Puri1, Matthew Gingo2* and Alison Morris3

1Division of General Internal Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

2Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

3Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

Corresponding Author:
Matthew Gingo
3459 Fifth Ave. NW628 MUH
Pittsburgh, PA 15213, USA
Tel: 412-624-3045
Fax: 412-624-8373
E-mail: [email protected]

Received Date: May 27, 2014; Accepted Date: July 09, 2014; Published Date: July 16, 2014

Citation: Puri A, Gingo M, Morris A (2014) Asthma in HIV-Infected Population: A Review of Respiratory Symptoms, Pulmonary Function Abnormalities and Pathophysiology. Epidemiol 4:164. doi:10.4172/2161-1165.1000164

Copyright: © 2014 Gingo M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Asthma is prevalent around the world, requiring frequent hospital admissions and resulting in significant morbidity. National surveillance for asthma in the United States estimated the prevalence of asthma from 2006-2008 to be approximately 7.3% in adults, with the prevalence being higher in females (8.9%) than males (5.5%). The pathophysiology of asthma is characterized by inflammation and hyper-responsiveness of lung bronchioles. There is emerging evidence indicating an association between asthma and human immunodeficiency virus (HIV) infection, but much remains to be learned. The article will review the prevalence of respiratory symptoms, pulmonary function abnormalities and asthma in the HIV-infected population and summarize recent research focusing on potential mechanisms linking the two disease processes. In addition, we review important asthma treatment considerations in HIV-infected individuals.

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