Astonishing Diversity of Natural Peroxides as Potential Therapeutic Agents
Valery M Dembitsky*
Institute of Drug Discovery, P.O. Box 45289, Jerusalem 91451, Israel
- Corresponding Author:
- Dembitsky VM
Institute of Drug Discovery
P.O. Box 45289, Jerusalem 91451, Israel
Tel: +972 526 877 444
E-mail: [email protected]
Received date: January 28, 2015, Accepted date: February 25, 2015, Published date: March 04, 2015
Citation: Dembitsky VM (2015) Astonishing Diversity of Natural Peroxides as Potential Therapeutic Agents. J Mol Genet Med 9:163. doi:10.4172/1747-0862.1000163
Copyright: © 2015 Dembitsky VM. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Peroxides are an interesting group among biological active natural compounds. These metabolites contain a peroxide group (-O-O-) in which each oxygen atom is bonded to the other oxygen and to another atom. β-Oxygen in hydroperoxide group is considered as more active. Present review describes research on more than 230 natural peroxides isolated from plants, algae, and fungi. Intensive searches for new classes of biologically active metabolites produced by terrestrial and marine origin have resulted in the discovery of dozens of compounds possessing high antimalarial, antibacterial, cytotoxic, and other pharmacological activities as an important source of leads for drug discovery.