alexa Asymptomatic Infection of Borrelia burgdorferi in Xinjiang, China | OMICS International | Abstract
ISSN: 2155-9597

Journal of Bacteriology & Parasitology
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Research Article

Asymptomatic Infection of Borrelia burgdorferi in Xinjiang, China

Yuhui Tan1*, Qin Hao4, Kanglin Wan4, Yong Liu2, He Sun2, Luhai Yu3, Yuhan Zhang1, Hui Dang1, Mingyuan Wang1, Yi Zhu1, Hetaer Mo1, Siya A1, Jiang Long1, Hongyan Li1, Yinuer Ma1 and Qin Li1

1Department of Neurology, Xinjiang Uygur Autonomous Region Hospital, Urumqi, China

2Department of Pediatrics, Xinjiang Uygur Autonomous Region Hospital, Urumqi, China

3Department of Clinical Pharmacy, Xinjiang Uygur Autonomous Region Hospital, Urumqi, China

4Chinese Center for Disease Control and Prevention, Beijing, China1Xinjiang

*Corresponding Author:
Yuhui Tan
Department of Neurology
Xinjiang Uygur Autonomous Region Hospital
No.91, Tian Chi Road, Urumqi, Xinjiang, China, 830001
Tel: 0991-8566015, 13579223523
Fax: 0991-8565302
E-mail: [email protected]

Received date: June 09, 2012; Accepted date: July 05, 2012; Published date: July 09, 2012

Citation: Tan Y, Hao Q, Wan K, Liu Y, Sun H (2012) Asymptomatic Infection of Borrelia burgdorferi in Xinjiang, China. J Bacteriol Parasitol 3:145. doi: 10.4172/2155-9597.1000145

Copyright: © 2012 Tan Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

The natural history of asymptomatic infection of Borrelia burgdorferi (B. burgdorferi) and genotype infected population of Xinjiang has been unclear. We report here, on the basis of molecular epidemiological studies on B. burgdorferi in population of Tacheng, the endemic area in Xinjiang China, the outcome of asymptomatic infection of B. burgdorferi and PCR result to B. burgdorferi in participants of a follow-up visit in 2006, based on the sero-epidemiological investigation of B. burgdorferi infection in 2002, and detected the serum anti-B. burgdorferi antibody levels in participants using western blot assay. In addition, urine samples were collected from participants at the time of follow-up and tested by nested PCR for the presence of B. burgdoferi DNA. Eight positive products were sequenced by the Borders Group Inc Company. We show that asymptomatic infection with B. burgdorferi occurred more frequently than clinical cases of Lyme disease. Sequencing analysis of the 5s-23SrRNA spacer region of Eight PCR-positive samples revealed that 7 were of B. garinii and 1 of B. afzelii, these genospecies are identical with those infecting local vectors.

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