alexa Autoantibodies Profile in Vitiligo
ISSN: 2376-0427

Dermatology and Dermatologic Diseases
Open Access

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Previously: Journal of Pigmentary Disorders

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Review Article

Autoantibodies Profile in Vitiligo

Kabir Magaji Hamid1,2*, Zelalem Kiros Bitsue2 and Abbas Mirshafiey3
1Department of Immunology, Faculty of Medical Laboratory Sciences, Usmanu Danfodiyo University Sokoto, P.M.B 2346, Nigeria
2Department of Immunology, School of Public Health, Tehran University of Medical Sciences-International Campus (TUMS-IC) Tehran-14155, Box: 6446, Iran
3Department of Immunology, School of Public Health, Tehran University of Medical Sciences, (TUMS) Tehran-14155, Box: 6446, Iran
Corresponding Author : Kabir Magaji Hamid
Department of Immunology, Faculty of Medical Laboratory Sciences
Usmanu Danfodiyo University Sokoto, P.M.B 2346, Nigeria
Tel: +989102159812
E-mail: [email protected]
Received April 14, 2015; Accepted May 15, 2015; Published May 25, 2015
Citation: Hamid KM, Bitsue ZK, Mirshafiey A (2015) Autoantibodies Profile in Vitiligo. Pigmentary Disorders 2:187. doi:10.4172/2376-0427.1000187
Copyright: © 2015 Hamid KM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

Vitiligo is one of the disease which is yet to understand its pathogenesis, however many studies associate this disease as an autoimmune. Detection of autoimmune cells in the serum, lesional and perilesional area of vitiligo patients gives more insight on the disease mechanism. Presence of autoantibodies against melanocytes antigens in vitiligo patients indicates an autoimmune involvement in the aetiology of the disease. Identification and characterization of vitiligo autoantibodies would pave the way for developing new laboratory test for diagnosis. Studying the autoantibodies profile can give an impression on the disease condition of vitiligo patients. We realized the need of research emphasis in this area as more is yet to be discovered. In this review we give an account on different autoantibodies and their associated autoantigens in vitiligo as another effort of providing an updated data for detail analysis.

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