alexa Autoimmune Hemolytic Anemia in a Patient with Acute Myelomonocytic Leukemia
ISSN: 2155-9864

Journal of Blood Disorders & Transfusion
Open Access

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Case Report

Autoimmune Hemolytic Anemia in a Patient with Acute Myelomonocytic Leukemia

Noha Essa, Shaimaa El-Ashwah, May Denewer, Yasmine Essam and Mohamed Mabed*

Division of Hematology, Oncology Center, Mansoura University, Egypt

*Corresponding Author:
Mohamed Mabed, MD, PhD
Division of Hematology
Oncology Center, Faculty of Medicine
Mansoura University, Egypt
Tel: 00201068595165
Fax: 002050 2370103
E-mail: [email protected]

Received date: December 17, 2015; Accepted date: January 19, 2016; Published date: January 22, 2016

Citation: Essa N, El-Ashwah S, Denewer M, Essam Y, Mabed M (2016) Autoimmune Hemolytic Anemia in a Patient with Acute Myelomonocytic Leukemia. J Blood Disord Transfus 7:336. doi:10.4172/2155-9864.1000336

Copyright: © 2016 Essa N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Autoimmune hemolytic anemia (AIHA) has been described in patients with lymphoid neoplasm with an etiologic relationship between the emergence of autoantibodies and lymphocyte dysfunction. Autoimmune disorders are less to develop in patients with other neoplasm like chronic myeloid leukemia, myelodysplastic syndrome or acute myeloid leukemia. Few reports have been documented the development of immune hemolytic anemia in patients with acute myeloid leukemia. We herein, present the case of de novo acute myelomonocytic leukemia associated with autoimmune hemolytic anemia. The patient has no previous medical history of anemia and Hb level at presentation was normal. She received chemotherapy containing Adriamycin plus Cytarabine. She showed marked improvement of anemia after steroid therapy with subsidence of all the clinical and laboratory manifestations of hemolysis when the patient went into remission. AIHA should be considered as one cause of anemia in

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