alexa Autologous Serum Eye Drop in Refractory Neurotrophic Co
ISSN: 2155-9570

Journal of Clinical & Experimental Ophthalmology
Open Access

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Case Report

Autologous Serum Eye Drop in Refractory Neurotrophic Corneal Ulcer: A Case Report

Poonam Lavaju1*, Sangeeta Shah1, Icchya Joshi2 and Aashish Raj Pant3

1Department of Ophthalmology, BP Koiral Institue of Health Sciences, Dharan, Nepal

2Biratnagar Eye Hospital, Biratnagar, Nepal

3Mechi Eye Hospital, Mechi, Nepal

*Corresponding Author:
Poonam Lavaju
Department of Ophthalmology
BP Koirala Institute of Health sciences, Dharan, Nepal
Tel: 00977-9852047026;
E-mail: [email protected]

Received Date: March 30, 2017; Accepted Date: April 17, 2017; Published Date: April 29, 2017

Citation: Lavaju P, Shah S, Joshi I, Pant AR (2017) Autologous Serum Eye Drop in Refractory Neurotrophic Corneal Ulcer: A Case Report. J Clin Exp Ophthalmol 8:649. doi: 10.4172/2155-9570.1000649

Copyright: © 2017 Lavaju P, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Purpose: To report a case of refractive neurotrophic corneal ulcer, treated successfully with 20% autologous serum eye drops.

Case Report: A 20 year old male presented with redness and foreign body sensation since three months associated with photophobia and progressive diminution of vision of both the eyes, right eye more than left, since 2 months. At presentation, the best corrected visual acuity in the right eye was 1/60 and left 6/12. Right eye showed cilliary congestion and epithelial defect of 4.5 × 1.5 mm with thinning (~80%). Left eye had diffuse superficial keratopathy with paracentral nebular corneal opacity. Corneal sensation was decreased with schirmer’s test I reading of 1 mm in both the eyes. With the provisional diagnosis of refractory neurotrophic corneal ulcer, 20% autologous serum eye drops was started in the right eye four hourly along with topical preservative free tear substitutes. After one week, there was dramatic improvement in the right eye with healed cornea and decrease in thinning.

Conclusion: Autologous serum eye drops is beneficial in the treatment of neurotrophic corneal ulcer and can prevent further complications.


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